Efficacy of epidural steroid injection with hypertonic solution for post-herpetic neuralgia
- Conditions
- Diseases of the nervous system
- Registration Number
- KCT0002845
- Lead Sponsor
- Asan Medical Center
- Brief Summary
Final thirty-six patients (NS: 17, HS: 19) were included in the intention-to-treat analysis. The estimated pain intensity decreased in both groups at one and three months after the procedure (P < 0.001), without a significant group difference. The estimated ISI and MQS were not significantly different at 1 month compared with baseline but significantly decreased at 3 months in each group (P < 0.001 and P < 0.001, respectively), without group differences. In addition, there was no difference between the groups on the GPES scale at one and three months after the procedure.
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Completed
- Sex
- All
- Target Recruitment
- 36
1) Age > 18yrs
2) Patients complaining of neuralgia even after 4 months of onset of herpes zoster
3) Postherpetic neuralgia involving cervical, thoracic and lumbar spinal nerve.
4) Numerical rating scale (NRS) > 6
5) Patients with postherpetic neuralgia who are not responsive to oral or intravenous form of analgesics
6) Patients who spontaneously agreed to join the study by themselves.
1) Patients who do not agreed to join the study.
2) Postherpetic neuralgia involving cranial and facial nerves.
3) Patients who had epidural steroid injection within 3 months prior to screening.
4) Pregnant or breast feeding patients.
5) Patients who are allergic to local anesthetics, contrast dye, steroid and hypertonic solution.
6) Patients with red flag signs (infection, cancer, coagulopathy, severe neurologic deficit, cauda equina syndrome)
7) Patients with uncontrolled medical or psychological diseases.
Study & Design
- Study Type
- Interventional Study
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method umeric rating scale(NRS)
- Secondary Outcome Measures
Name Time Method Insomnia Severity Index;, Global perceived effect 7-point scale,;current medication