Assessment of correlation of BRCA1 / BRCA2 mutation with Prakruti and Artava- vaha Srotas in breast cancer patients.
Trial Snapshot
- Phase
- Not Applicable
- Status
- Not yet recruiting
- Sponsor
- Enrollment
- 60
- Locations
- 1
- Primary Endpoint
- 1.a Variation in body constitution in mutated and non mutated breast cancer patients wrt physiological, physical and mental aspects.
Study Overview
Brief Summary
The present study is an observational study of female breast cancer patients who are tested for BRCA 1 and BRCA 2 mutations and their assessment will be done on the basis of their Prakriti and Aartavavaha Srotas (menstrual and obstetric history). The primary objective is to study the association between positive and negative BRCA 1 and BRCA 2 mutated breast cancer patients with their Prakriti and status of Aartavavaha Srotas. The secondary objective will include study of association between Prakriti and various components of mutation analysis like gene (transcript), location, variant, zygosity, etc.
Study Design
- Study Type
- Observational
Eligibility Criteria
- Ages
- 25.00 Year(s) to 70.00 Year(s) (—)
- Sex
- Female
Inclusion Criteria
- •Female breast cancer patients of stage I, II and III with and without BRCA 1 and BRCA 2 mutations.
Exclusion Criteria
- •Female breast cancer patients of stage IV, Multiple primary malignancies Male breast cancer patients Breast cancer patients having mutations other than BRCA 1 or BRCA 2.
Outcomes
Primary Outcomes
1.a Variation in body constitution in mutated and non mutated breast cancer patients wrt physiological, physical and mental aspects.
Time Frame: Data regarding the Prakriti and Aartava-vaha Srotasa of the patients will be collected in the beginning of the study i.e. at baseline. This study being observational study, no specific timepoints are required.
1.b Variation in female reproductive system wrt menstruation and parity
Time Frame: Data regarding the Prakriti and Aartava-vaha Srotasa of the patients will be collected in the beginning of the study i.e. at baseline. This study being observational study, no specific timepoints are required.
Secondary Outcomes
- Comparison between components of mutation analysis such as gene transcript, location, variant, zygosity, etc with Prakruti(This study being observational study, only baseline time point is required.)
Investigators
DR SAMEER NARAYAN GORE