Assessment of correlation of BRCA1 / BRCA2 mutation with Prakruti and Artava- vaha Srotas in breast cancer patients.
试验速览
- 阶段
- 不适用
- 状态
- 尚未招募
- 发起方
- 入组人数
- 60
- 试验地点
- 1
- 主要终点
- 1.a Variation in body constitution in mutated and non mutated breast cancer patients wrt physiological, physical and mental aspects.
研究概览
简要总结
The present study is an observational study of female breast cancer patients who are tested for BRCA 1 and BRCA 2 mutations and their assessment will be done on the basis of their Prakriti and Aartavavaha Srotas (menstrual and obstetric history). The primary objective is to study the association between positive and negative BRCA 1 and BRCA 2 mutated breast cancer patients with their Prakriti and status of Aartavavaha Srotas. The secondary objective will include study of association between Prakriti and various components of mutation analysis like gene (transcript), location, variant, zygosity, etc.
研究设计
- 研究类型
- Observational
入排标准
- 年龄范围
- 25.00 Year(s) 至 70.00 Year(s)（—）
- 性别
- Female
入选标准
- •Female breast cancer patients of stage I, II and III with and without BRCA 1 and BRCA 2 mutations.
排除标准
- •Female breast cancer patients of stage IV, Multiple primary malignancies Male breast cancer patients Breast cancer patients having mutations other than BRCA 1 or BRCA 2.
结局指标
主要结局
1.a Variation in body constitution in mutated and non mutated breast cancer patients wrt physiological, physical and mental aspects.
时间窗: Data regarding the Prakriti and Aartava-vaha Srotasa of the patients will be collected in the beginning of the study i.e. at baseline. This study being observational study, no specific timepoints are required.
1.b Variation in female reproductive system wrt menstruation and parity
时间窗: Data regarding the Prakriti and Aartava-vaha Srotasa of the patients will be collected in the beginning of the study i.e. at baseline. This study being observational study, no specific timepoints are required.
次要结局
- Comparison between components of mutation analysis such as gene transcript, location, variant, zygosity, etc with Prakruti(This study being observational study, only baseline time point is required.)
研究者
DR SAMEER NARAYAN GORE