"Clinical Characteristics, Comorbidities and Outcome of Critically Sick Patients With COVID-19

Completed

• Conditions: COVID-19 Pneumonia
• Interventions: Combination Product: Patients with COVID-19 Pneumonia

• Registration Number: NCT05249803
• Lead Sponsor: FMH College of Medicine and Dentistry

Brief Summary

COVID-19, caused by severe acute respiratory syndrome corona virus 2 (SARS-CoV-2), is a multisystem disease which primarily involves the respiratory tract. The first case of COVID-19 was identified in late 2019 in the province of Wuhan, China which was followed by the rapid spread of the disease globally, becoming a present-day pandemic.

Objectives: The aim of this study was to describe the clinical characteristics, comorbidities and outcome of the critically sick patients with COVID-19 pneumonia admitted in ICU of a tertiary care hospital in Lahore.

Detailed Description

Objectives: The aim of this study was to describe the clinical characteristics, comorbidities and outcome of the critically sick patients with COVID-19 pneumonia admitted in ICU of a tertiary care hospital in Lahore.

Material \& Methods:

Study design: Retrospective study. Study Settings: Study was conducted in Fatima Memorial Hospital, Lahore. Study Duration: Study was conducted on Covid-19 patients who were admitted from March 2021 to August 2021.

Study Timeline

• Study Start: 2021-03-01
• Primary Completion: 2021-08-31
• Study Completion: 2021-12-31
• Status Verified: 2022-02
• Study First Submitted: 2022-02-01
• Study First Submitted QC: 2022-02-21
• Last Update Submitted: 2022-02-21
• Study First Posted: 2022-02-22
• Last Update Posted: 2022-02-22

Recruitment & Eligibility

• Status: COMPLETED
• Sex: All
• Target Recruitment: 133

Inclusion Criteria

• Critically sick patients with COVID-19 Pneumonia
• All admitted ICU patients with a diagnosis of COVID-19 pneumonia
• Patients having positive reverse transcriptase PCR for COVID-19
• Patients with High-resolution computed tomography (HRCT) chest findings suggestive of COVID-related lung injury
• All patients above 16 years of age with both genders( males and females)

Exclusion Criteria

• All patients with PCR negative with mild symptoms
• Patients with No signs of COVID-19 pneumonia on HRCT chest

Study & Design

• Study Type: OBSERVATIONAL
• Study Design: Not specified

Arm && Interventions

Group	Intervention	Description
Patients with COVID-19 pneumonia	Patients with COVID-19 Pneumonia	These patients were admitted in ICU for management of Covid-19 pneumonia usual care was offered to all patients

Primary Outcome Measures

Name	Time	Method
Mortality	6 months	The primary endpoint of the study will be to assess the ICU mortality (in percentages% and Numbers) of critically sick patients with COVID-19 pneumonia admitted to the intensive care unit

Secondary Outcome Measures

Name	Time	Method
Comorbidities	6 months	we will assess various comorbidities in critically sick patients with COVID-19 pneumonia admitted to the intensive care unit

Trial Locations

Locations (1)

Fatima Memorial Hospital College of Medicine & Dentistry; 🇵🇰 Lahore, Punjab, Pakistan