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Clinical Trials/NCT06286618
NCT06286618
Completed
Not Applicable

Moving to Integrated and Holistic Disease Prevention Among Underserved Mississippians

University of Southern Mississippi1 site in 1 country24 target enrollmentSeptember 1, 2022

Overview

Phase
Not Applicable
Intervention
Not specified
Conditions
Cardiovascular Diseases
Sponsor
University of Southern Mississippi
Enrollment
24
Locations
1
Primary Endpoint
Participant Burden
Status
Completed
Last Updated
last year

Overview

Brief Summary

The objective for the study is to implement a pilot study to establish essential components to address diet quality in healthcare settings and examine what value an integrated service model delivery has for the primary prevention of cardiometabolic diseases with an initial focus on dietary behaviors. This objective will be met by 1: Utilizing a multiphase optimization study design to select and optimize essential components to address diet behaviors and 2: Comparing an integrated and referral-based delivery model for healthcare-based strategies that address structural and psychosocial barriers to a healthy diet for racial/ethnic minority, marginalized and disadvantaged background young to middle aged adult populations in Mississippi.

Detailed Description

The study is designed based on the multiphase optimization strategy (MOST), which includes three phases to prepare or screen, optimize, and evaluate multiple components of an intervention. During first optimization phase, study team will conduct essential component selection by pilot testing three common strategies used in healthcare settings to deliver structural and psychosocial interventions that address diet behaviors. The second optimization phase will include pilot testing to examine the optimization of delivery mode for the essential components identified in first phase. In each phase, participants between 25 to 50 years of age who are at risk for CVD-related premature mortality will be recruited to complete a 3-month intervention in a community based clinical setting in Mississippi. The proposed project will provide foundational knowledge for components and delivery models that are the most essential and cost-effective to improve dietary behaviors among racial/ethnic minority and disadvantaged background populations in Mississippi.

Registry
clinicaltrials.gov
Start Date
September 1, 2022
End Date
September 24, 2024
Last Updated
last year
Study Type
Interventional
Study Design
Crossover
Sex
All

Investigators

Responsible Party
Sponsor

Eligibility Criteria

Inclusion Criteria

  • 25 to 50 years of age
  • cardiovascular disease-related premature mortality risk (people living with HIV/AIDS or diagnosed with or familial risk for diabetes, hypertension, obesity, or Metabolic syndrome)
  • internet access
  • Jackson (Mississippi) metropolitan statistical area residency

Exclusion Criteria

  • cancer with active treatment
  • chronic obstructive pulmonary disorder, emphysema, cystic fibrosis or any other major lung disease
  • liver or kidney dysfunction, end-stage renal disease, active hepatitis,
  • celiac disease, colitis, or other gastrointestinal disorders
  • current pregnancy or within six months postpartum at baseline
  • heavy drinking
  • unintentional weight loss of more than 5% of body weight within the past six months
  • recent (in the past 6 months) heart attack, stroke or other major heart surgery or event
  • eating disorders (anorexia or bulimia nervosa)
  • currently being treated for a fungus, bacteria, viral, or other infection due to weak immune system

Outcomes

Primary Outcomes

Participant Burden

Time Frame: up to 12 weeks

An existing validated tool designed to assess research participant burden (Lingler et al., 2014) for cultural and contextual appropriateness; the tool includes 21 items assessed on a 5-point Likert agreement scale and the final adapted items will be summed for a total score. Higher scores mean a worse outcome.

Secondary Outcomes

  • cost effectiveness(3 months)
  • session attendance(3 months)
  • diet quality(up to 3 months)

Study Sites (1)

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