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Comparison of the Immunogenicity of ChAdOx1 nCoV-19 (COVID-19) Vaccine against the Wild-Type and Delta Variant in Kidney Transplant Recipients and Healthy Volunteers

Recruiting
Conditions
Immune response after ChAdOx1 nCoV-19 Vaccine in kidney transplant patients compared to healthy volunteers.
Immune response, ChAdOx1 nCoV-19 Vaccine, kidney transplant patients, Wuhan Strain, B.1.617.2 (Delta) Variant, antibody, T-cell response
Registration Number
TCTR20211025004
Lead Sponsor
Kao Tun Roke Foundation
Brief Summary

Not available

Detailed Description

Not available

Recruitment & Eligibility

Status
Recruiting
Sex
All
Target Recruitment
200
Inclusion Criteria

1. Adult (age >= 18 years old), 2.Kidney transplant recipients, 3. Recipients 2 doses of ChAdOx1 nCoV-19 vaccine

Exclusion Criteria

1. Refuse to participate, 2.Infected with COVID-19 during the study period, 3. Recipients of intravenous immunoglobulin

Study & Design

Study Type
Observational
Study Design
Not specified
Primary Outcome Measures
NameTimeMethod
Immunogenicity 2-6 weeks after vaccination Antibody response and T-cell response
Secondary Outcome Measures
NameTimeMethod
Associated factors of antibody response After the results of immune response Statistical analysis,Associated factors of T-cell response After the results of immune response Statistical analysis,Safety and adverse reactions after vaccination After completion of each dose of vaccination Statistical analysis
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