Anti-inflammatory Therapy Following Selective Laser Trabeculoplasty
Not Applicable
Completed
- Conditions
- Pseudoexfoliation GlaucomaPrimary Open Angle Glaucoma
- Interventions
- Registration Number
- NCT00485108
- Lead Sponsor
- Queen's University
- Brief Summary
The type of anti-inflammatory medication used post selective laser trabeculoplasty (SLT) may have an impact on the intra-ocular pressure (IOP) lowering effect of SLT. This study will evaluate the IOP lowering effect of SLT following the topical administration of one of the following: prednisolone 1%, ketorolac 0.5% or artificial tears.
- Detailed Description
Patients who have been chosen to undergo SLT for glaucoma will be randomized to receive one of prednisolone 1%, ketorolac 0.5% or artificial tears four times a day for 5 days following administration of the laser treatment. The IOP will be measured at various time points following SLT: 1 hour, 2 days, 1 week, 1 month, 3 months, 6 months, and 1 year.
Recruitment & Eligibility
- Status
- COMPLETED
- Sex
- All
- Target Recruitment
- 120
Inclusion Criteria
- primary open angle glaucoma, pseudo exfoliation glaucoma
Exclusion Criteria
- previous incisional glaucoma surgery
Study & Design
- Study Type
- INTERVENTIONAL
- Study Design
- PARALLEL
- Arm && Interventions
Group Intervention Description 1 prednisolone 1% Prednisolone 1% eye drop 2 ketorolac 0.5% ketorolac 0.5% eye drop 3 Artificial Tears (Methyl cellulose drops) Artificial Tears (methyl cellulose eye drop)
- Primary Outcome Measures
Name Time Method Intraocular pressure lowering effect 1 hour, 2 days, 1 month, 3 months, 6 months and 1 year
- Secondary Outcome Measures
Name Time Method intraocular pressure elevation 1 hour, 2 days, 1 month
Trial Locations
- Locations (1)
Queen's University
🇨🇦Kingston, Ontario, Canada