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Clinical Trials/NCT06386276
NCT06386276
Recruiting
Not Applicable

Surgical TReatment of Women With Deep ENDometriosis Infiltrating the Sigmoid Colon and/or the Rectum. A Monocentric Archive

Casa di Cura Privata 'Malzoni - Villa dei Platani' S.P.A.1 site in 1 country250 target enrollmentOctober 11, 2023

Overview

Phase
Not Applicable
Intervention
Not specified
Conditions
Deep Endometriosis
Sponsor
Casa di Cura Privata 'Malzoni - Villa dei Platani' S.P.A.
Enrollment
250
Locations
1
Primary Endpoint
To assess the rate of recurrence
Status
Recruiting
Last Updated
2 years ago

Overview

Brief Summary

TrEnd trial is aimed to collect data from consecutive patients undergoing segmental sigmoid colon/rectal resection for deep endometriosis. The main purpose of this project is to gather a large series of cases treated using standardized surgical procedures, allowing a precise evaluation of complications and long-term outcomes.

Registry
clinicaltrials.gov
Start Date
October 11, 2023
End Date
June 30, 2029
Last Updated
2 years ago
Study Type
Observational
Sex
Female

Investigators

Sponsor
Casa di Cura Privata 'Malzoni - Villa dei Platani' S.P.A.
Responsible Party
Principal Investigator
Principal Investigator

Francesca Falcone

Medical Doctor

Casa di Cura Privata 'Malzoni - Villa dei Platani' S.P.A.

Eligibility Criteria

Inclusion Criteria

  • age \>/= 18 years;
  • presence of deep endometriotic nodule(s) infiltrating the tunica muscularis of the sigmoid colon/rectum.

Exclusion Criteria

  • age \<18 years:
  • presence of coexisting inflammatory bowel disease;
  • patients who have received previous pelvic radiotherapy.

Outcomes

Primary Outcomes

To assess the rate of recurrence

Time Frame: 10 years

Rate/percentage

To document the surgical strategies adopted for treating patients with deep endometriosis undergoing to sigmoid colon/rectal resection

Time Frame: 10 years

Percentage

To assess the rate of conversion to open surgery

Time Frame: 10 years

Rate/percentage

To assess the rate of endometriosis-free bowel resection margins

Time Frame: 10 years

Rate/percentage

To assess the rate of complications

Time Frame: 10 years

Rate/percentage

Secondary Outcomes

  • To assess the operating time(10 years)
  • To assess the gastrointestinal function recovery(10 years)
  • To assess the reproductive outcomes(10 years)
  • To assess the intraoperative blood loss(10 years)
  • To assess the duration of hospital stay(10 years)

Study Sites (1)

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