Treatment of acne with dapsone gel plus oral isotretinoi
Not Applicable
- Conditions
- Acne Vulgaris.Acne Vulgaris
- Registration Number
- IRCT2014011015509N1
- Lead Sponsor
- Vice Chancellor for Research, Isfahan University of Medical Sciences
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Complete
- Sex
- All
- Target Recruitment
- 58
Inclusion Criteria
age between 18 and 25 years old; moderate to severe facial acne; absence of contraindications to treatment with tablets of isotretinoin and 5% dapsone gel.
Exclusion criteria: acne secondary to other problems; pregnancy or intention to become pregnant; breastfeeding; another dermatological disease of the face; G6PD deficiency; and known hypersensitivity to dapsone or isotretinoin.
Exclusion Criteria
Not provided
Study & Design
- Study Type
- interventional
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method Acne vulgaris lesions. Timepoint: Baseline, weeks 4, weeks 8, weeks 12. Method of measurement: Total Acne lesion Count( TLC.) and The Global Acne Assessment Score for each patient.
- Secondary Outcome Measures
Name Time Method Side effects of drug. Timepoint: Every 4 weeks. Method of measurement: Clinical evaluation-laboratory test.