The Effect of Transcutaneous Electrical Nerve Stimulation on Pain During Propofol Injection
试验速览
- 阶段
- 不适用
- 入组人数
- 80
- 试验地点
- 1
- 主要终点
- pain during propofol injection
研究概览
简要总结
Propofol, an intravenous sedative agent, frequently produces pain during injection. This study was designed to investigate whether transcutaneous electrical nerve stimulation could reduce pain during propofol injection.
in minimizing propofol injection pain.
详细描述
Twenty min after transcutaneous electrical nerve stimulation, the electrodes were removed and propofol 0.5 mg/kg was administered at the rate of 0.5 ml/sec using syringe pump. Propofol injection pain was evaluated by a study blinded anesthesiologist using a four point scale: 0=no (negative response to questioning), 1=mild pain (pain reported only in response to questioning without any behavioral sings), 2=moderate pain (pain reported in response to questioning and accompanied by a behavioral signs or pain reported spontaneously without questioning, 3=severe pain (strong vocal response or response accompanied by facial grimacing, arm withdrawal or tears).
研究设计
- 研究类型
- Interventional
- 分配方式
- Randomized
- 干预模型
- Parallel
- 主要目的
- Prevention
- 盲法
- Single (Investigator)
盲法说明
Two electrodes were attached to the radial side of dominant forearm. In the placebo group the TENS device had no current output although the power "on" indicator light remained active.
入排标准
- 年龄范围
- 19 Years 至 70 Years（Adult, Older Adult）
- 性别
- All
- 接受健康志愿者
- 否
入选标准
- 未提供
排除标准
- •American Society of Anesthesiologists physical status classification > 3
- •Patient with a history of allergy to drugs
- •Patient who takes opioid, sedative, anticonvulsant
- •Patient with a history of neurologic disease and psychological disorders
- •patient with skin problem
- •Patient with pacemaker or electric medical device
- •pregnancy
研究组 & 干预措施
transcutaneous electrical nerve stimulation group
Transcutaneous electrical nerve stimulation was givent via two electrodes on the venous cannulation site 20 min before propofol injection
干预措施: transcutaneous electrical nerve stimulation (Device)
control group
No transcutaneous electrical nerve stimulation was not given via two electrodes on the venous cannulation site 20 min before propofol injection
干预措施: Placebo transcutaneous electrical nerve stimulation (Device)
结局指标
主要结局
pain during propofol injection
时间窗: 15 seconds
Propofol injection pain was evaluated by a study blinded anesthesiologist using a four point scale
次要结局
未报告次要终点
研究者
Younghoon Jeon
Professor
Kyungpook National University Hospital