Impact of Fluid Resuscitation Protocol on the Incidence of Reoperation for Bleeding After Emergency Cardiopulmonary Bypass Grafting

Completed

• Conditions: Resternotomy
• Interventions: Other: Assessment of reason for avoidance of resternotomy; Other: Assessment of reason for resternotomy

• Registration Number: NCT04533698
• Lead Sponsor: University Hospital, Basel, Switzerland

Brief Summary

This is a retrospective data analysis of patients that underwent elective or emergency cardiopulmonary bypass. Resternotomy due to bleeding is frequent after sternotomy. Also due to implementation of Argipressin into clinical practice fluid resuscitation protocol has changed to more vasopressors and less fluid within the past five years. The investigators want to explore the influence of volume resuscitation protocol on incidence of rethoracotomy during the past twenty years.

Detailed Description

Not available

Study Timeline

• Study Start: 2009-01-01
• Study First Submitted: 2020-08-26
• Study First Submitted QC: 2020-08-26
• Study First Posted: 2020-08-31
• Primary Completion: 2021-05-31
• Study Completion: 2024-06-30
• Status Verified: 2025-04
• Last Update Submitted: 2025-04-03
• Last Update Posted: 2025-04-04

Recruitment & Eligibility

• Status: COMPLETED
• Sex: All
• Target Recruitment: 265

Inclusion Criteria

• All patients that underwent elective or emergency aortocoronary bypass at the University Hospital Basel between 2009 and 2020.

Exclusion Criteria

• None.

Study & Design

• Study Type: OBSERVATIONAL
• Study Design: Not specified

Arm && Interventions

Group	Intervention	Description
No resternotomy	Assessment of reason for avoidance of resternotomy	-
Resternotomy	Assessment of reason for resternotomy	-

Primary Outcome Measures

Name	Time	Method
Resternotomy	7 days	Resternotomy yes or no after elective or emergency aortocoronary bypass