Comparing Patients After ESWL Treated With Ureteral Stents Versus Expulsion Therapy With Tamsulosin
Phase 2
- Conditions
- Upper Tract Ureterolithiasis
- Registration Number
- NCT00478998
- Lead Sponsor
- Hadassah Medical Organization
- Brief Summary
The purpose of this study is to see whether patients undergoing ESWL, for upper tract urinary stones between 1.5-2.0cm, may be treated by expulsion therapy(Tamsulosin) instead of inserting ureteral stents .
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- UNKNOWN
- Sex
- All
- Target Recruitment
- Not specified
Inclusion Criteria
- Patients above 18 yrs of age.
- Single urolithiasis up to 2 cm.
- Kidney/ureters that haven't undergone previous ESWL or stent insertion.
- Normal renal function (creatinine below 100mmo1/1).
- Sterile urine culture.
- Normal CBC, blood electrolytes and coagulation studies.
- Radioopaque stones.
Exclusion Criteria
- More than one stone per kidney unit.
- Patients receiving steroids, NSAIDS, calcium channel blockers or alpha blockers on a regular basis.
- Anatomical anomalies or uromechanical obstruction.
- Single kidney.
- Cystinuria.
- Soldiers or pregnant women.
- Patients under 18 year
Study & Design
- Study Type
- INTERVENTIONAL
- Study Design
- PARALLEL
- Primary Outcome Measures
Name Time Method stone status at 3 month . stone free
- Secondary Outcome Measures
Name Time Method
Related Research Topics
Explore scientific publications, clinical data analysis, treatment approaches, and expert-compiled information related to the mechanisms and outcomes of this trial. Click any topic for comprehensive research insights.
What molecular mechanisms underlie Tamsulosin's efficacy in ureteral stone expulsion compared to stent placement post-ESWL?
How does Tamsulosin compare to ureteral stents in managing upper tract ureterolithiasis after extracorporeal shock wave lithotripsy?
Are there specific biomarkers that predict successful stone expulsion with Tamsulosin versus stent placement in NCT00478998?
What are the potential adverse events associated with Tamsulosin expulsion therapy versus ureteral stent placement in urolithiasis patients?
How do combination therapies involving Tamsulosin and other alpha-blockers compare to stent placement for post-ESWL stone management?
Trial Locations
- Locations (1)
Hadassah Medical Organization
🇮🇱Jerusalem, Israel
Hadassah Medical Organization🇮🇱Jerusalem, IsraelMordechai Duvdevani, MDPrincipal Investigator