DEteCTing gout, with or without a needle
Recruiting
- Conditions
- Gout
- Registration Number
- NL-OMON24638
- Lead Sponsor
- Performer: Meander Medical Center
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Recruiting
- Sex
- Not specified
- Target Recruitment
- 100
Inclusion Criteria
Age > 18 years
-Mono or oligo arthritis (2-3 swollen joints)
Exclusion Criteria
-Polyarthritis (¡Ý4 swollen joint);
-Chrystal proven gout in history
Study & Design
- Study Type
- Interventional
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method The sensitivity and specificity (95% CI) of DECT scanning for the detection of MSU deposition will be calculated. The area under receiver operating characteristic curve(AUC-ROC) will be employed to evaluate the screening method’s performance.<br>
- Secondary Outcome Measures
Name Time Method a)Identify the clinical features and laboratory variables that affect the primary outcome measure of positive DECT scan for lesions suggestive of uric acid deposition in patients with acute mono or oligo arthritis.<br /><br>b)Establish the additive value of ultrasound guided joint aspiration in patients in whom the first aspirate demonstrated no microscopic MSU and /or no synovial fluid<br /><br>c)Establish the additive value of ultrasound guided joint aspiration of DECT lesions suggestive of gout in patients in whom the earlier aspirate(s) demonstrated no microscopic MSU and /or no synovial fluid.<br /><br>d)Cost effectiveness analysis of different diagnostic strategies.<br /><br>e)Patient satisfaction: What does the patient experience as the most patient-friendly way of diagnosing gout: DECT scan, ultrasound-guided joint aspiration or blind aspiration?<br>