Prevention of acute respiratory problems in trauma patients

Phase 3

• Conditions: Acute Respiratory Distress Syndrome.; Acute respiratory distress syndrome

• Registration Number: IRCT20210711051839N1
• Lead Sponsor: Mashhad University of Medical Sciences

Brief Summary

Not available

Detailed Description

Not available

Study Timeline

• Results First Posted: 1900-01-01
• Last Update Posted: 29 November 2021

Recruitment & Eligibility

• Status: Complete
• Sex: All
• Target Recruitment: 62

Inclusion Criteria

Age between 18 and 65 years
Trauma patients at risk for ARDS who have lips=4 based on lung injury prediction score (lips)

Exclusion Criteria

Not having written informed consent.
Patients with adrenal insufficiency.
Patients with inflammation of the blood vessels.
Patients with intolerance to methylxanthine and pentoxifylline.
Patients who can not be prescribed the drug orally.
Occurrence of possible drug-related side effects if dangerous or intolerable to the patient.

Study & Design

• Study Type: interventional
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
Incidence of acute respiratory distress syndrome. Timepoint: During the study and at the end of the study. Method of measurement: Diagnosis based on criteria for diagnosing acute respiratory distress syndrome.;Respiration rate. Timepoint: At baseline and during the receive of the medication. Method of measurement: Cardiac Monitoring.;Heart rate. Timepoint: At baseline and during the receive of the medication. Method of measurement: Cardiac Monitoring.;Continuous pulse oximetry. Timepoint: At baseline and during the receive of the medication. Method of measurement: Capnography.;Blood pressure. Timepoint: At baseline and during the receive of the medication. Method of measurement: Cardiac Monitoring.;Blood gas factors. Timepoint: At baseline and during the receive of the medication. Method of measurement: Capnography.