EUCTR2011-005526-22-AT进行中（未招募）不适用
Tissue concentration of cefazolin and linezolid in sternal spongiosa in elective coronary artery bypass grafting: an in-vivo microdialysis study - Bone antibiotic concentration in CABG
相关药物
试验速览
- 阶段
- 不适用
- 状态
- 进行中（未招募）
研究概览
简要总结
暂无简介。
研究设计
- 研究类型
- Interventional clinical trial of medicinal product
入排标准
- 性别
- All
入选标准
- •-Written informed consent
- •-Planned coronary artery bypass grafting
- •-Planned used of cardiopulmonary bypass
- •-Age = 18 and = 90 years
- •-No pre-existing liver or kidney disease
- •-Left ventricular ejection fraction > 40%
- •-No pre-existing osteoporosis requiring therapy
- •Are the trial subjects under 18? no
- •Number of subjects for this age range:
- •F.1.2 Adults (18-64 years) yes
- •F.1.2.1 Number of subjects for this age range 10
- •F.1.3 Elderly (>=65 years) yes
- •F.1.3.1 Number of subjects for this age range 10
排除标准
- •-Preoperative antibiotic treatment
- •-Preoperative signs of infection
- •-Inability to give informed consent or missing informed consent
- •-Know allergy to cephalosporins, penicillin or Linezolid
- •-Re-operation
- •-Additional planned valve surgery
- •-Preoperative renal replacement therapy
- •-BMI > 40
- •-Long standing diabetes mellitus (> 7 years)
- •-Preoperative osteoporosis requiring therapy
- •-Age <18 or >90
- •-Chronic severe liver or renal insufficiency
- •-Childbearing potential
- •-Drug or alcohol abuses
- •-Psychiatric disease
- •-Treatment with MAO – inhibiting or serotonergic medication
研究者
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