The European CUP trial: a randomised trial in adults with poor risk relapsed follicular non-hodgkin's lymphoma
Completed
- Conditions
- ymphoma (non-Hodgkin's)CancerLymphoma (non-Hodgkin's)
- Registration Number
- ISRCTN46399359
- Lead Sponsor
- Baxter AG (Switzerland)
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Completed
- Sex
- Not specified
- Target Recruitment
- 0
Inclusion Criteria
1. Relapsed follicular non-Hodgkin's lymphoma, after a first or subsequent remission, requiring therapy because of at least one of the following:
1.1. B symptoms
1.2. Rapidly progressive disease
1.3. Bone marrow failure
1.4. Life threatening organ failure
2. Aged 15 - 65 years
3. No central nervous system (CNS) involvement
4. No previous radiotherapy greater than 2000 cGy to the mediastinum or abdomen, precluding total body irradiation
5. No previous myeloablative therapy
6. No prior malignancies, except non-melanomatous skin cancer or cervical carcinoma stage I
7. Adequate cardiac, neurologic, liver and renal function
8. No evidence of histlogically proven transformation
Exclusion Criteria
Not provided at time of registration
Study & Design
- Study Type
- Interventional
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method ot provided at time of registration
- Secondary Outcome Measures
Name Time Method ot provided at time of registration