Prevention of dementia using mobile phone applications: a randomised controlled trial

AMC0 个研究点目标入组 2,400 人2019年6月24日

概览

2021 Protocol article in https://pubmed.ncbi.nlm.nih.gov/34108173/ (added 13/08/2021) 2022 Other publications in https://pubmed.ncbi.nlm.nih.gov/36414280/ qualitative pre-results (added 28/11/2022) 2024 Results article in https://doi.org/10.1016/s2666-7568(24)00068-0 (added 20/05/2024)

注册库

who.int

开始日期

2019年6月24日

结束日期

2023年4月30日

最后更新

去年

研究类型

Interventional

性别

All

发起方

•1\. Age \= 55 years \- 75 years
•2\. Good proficiency of the national language (English in UK, Mandarin in China)
•3\. Possession of a smartphone
•4\. Persons who currently don’t have good access to preventive health care, including Low SES in the UK (Sussex and Greater Cambridge areas), operationalised as living in a postal code area ranked as equal to or less than the 3rd decile of the index of multiple deprivation (IMD) OR inhabitant of the Greater Beijing area irrespective of SES.
•5\. \= two dementia risk factors defined as:
•5\.1\. Manifest cardiovascular disease, as diagnosed by specialist or general practitioner
•5\.2\. Lack of physical exercise (self\-reported), defined as below the World Health Organization (WHO) norm (five times a week 30 minutes or a total of 150 minutes per week of intermediate exercise)
•5\.3\. Active smoking (self\-reported use of any sort of tobacco in any quantity)
•5\.4\. Hypertension, defined by any of the following:
•5\.4\.1\. Diagnosis by specialist or general practitioner.

•1\. Previously diagnosed with dementia by a specialist or general practitioner
•2\. Mini Mental State Examination (MMSE) \< 24
•3\. Any condition expected to limit 18\-months compliance and follow\-up, including metastasised malignancy or other terminal illness
•4\. Smartphone illiteracy, defined as not able to send a message from a smartphone
•5\. Visual impairment interfering with operation of a smartphone
•6\. Participating in another RCT
•7\. Present alcohol or illicit drug abuse; binge drinking is not an exclusion criterion – this is a potential target for behaviour change