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DROTAVERINE HYDROCHLORIDE VERSUS HYOSCINE BUTYLBROMIDE IN REDUCING FIRST STAGE OF LABOUR AMONG NULLIPARAE : A RANDOMIZED CONTROLLED TRIA

Not Applicable
Conditions
Pregnancy and Childbirth
Registration Number
PACTR202206902932545
Lead Sponsor
nenna S Nweke
Brief Summary

Not available

Detailed Description

Not available

Recruitment & Eligibility

Status
Complete
Sex
Female
Target Recruitment
165
Inclusion Criteria

1.Nulliparae
2.Women who consented to participate in the study
3.Women with fetus in cephalic presentation
4.Singleton fetus with no evidence of maternal or fetal distress.
5.Women with no contraindication to vaginal delivery.
6.Term pregnancies with intact or ruptured membranes
7.Cervical dilatation of 4-5 cm only
8.Spontaneous or induced labour
9.Patients on epidural

Exclusion Criteria

1 Women with abnormal fetal presentation.
2. Women in latent phase of labour.
3. Preterm / term premature rupture of membranes.
4. Antepartum haemorrhage.
5. Those who refused to consent.
6. Previous uterine scar or surgery.
7. Huge fibroid in pregnancy.
8. Multiple gestations.
9. Multiparous or grand multiparous patients.
10. Medical diseases in pregnancy such as severe preeclampsia/eclampsia and others.
11. History of cervical surgery.
12. Hypersensitivity to drotaverine hydrochloride.
13. Any contraindication to vaginal delivery

Study & Design

Study Type
Interventional
Study Design
Not specified
Primary Outcome Measures
NameTimeMethod
•To determine the efficacy of drotaverine hydrochloride versus hyoscine butyl bromide in reducing the duration of first stage of labour among nulliparous women
Secondary Outcome Measures
NameTimeMethod
•To determine the rate of cervical dilatation in the first stage of labour, after administration of drotaverine hydrochloride (in one group) and hyoscine butylbromide (in another group).<br>•To determine the side effects of these drugs on the mother and the baby.<br>•To compare the rate of cervical dilatation and side effects to the mother and baby following the use of drotaverine hydrochloride and hyoscine butylbromide.<br>•To compare participants’ satisfaction with the use of drotaverine hydrochloride and hyoscine butyl bromide during labour.<br>
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