EUCTR2008-003396-52-FR进行中（未招募）1 期
Randomized phase III study of neoadjuvant chemotherapy followed by surgery vs. concomitant radiotherapy and chemotherapy in FIGO Ib2, IIa > 4 cm or IIb cervical cancer.
European Organisation for Research and Treatment of Cancer0 个研究点目标入组 626 人开始时间: 2010年9月27日最近更新:
适应症
试验速览
- 阶段
- 1 期
- 状态
- 进行中（未招募）
- 发起方
- 入组人数
- 626
研究概览
简要总结
暂无简介。
研究设计
- 研究类型
- Interventional clinical trial of medicinal product
入排标准
- 性别
- Female
入选标准
- •- Cervical carcinoma of following histological types: squamous cell carcinoma, adenosquamous cell or adenocarcinoma
- •- FIGO stage Ib2, IIa >4cm or IIb
- •- WHO performance status of 0-2
- •- 18 - 75 years
- •- ANC > 1.5 x 109/l, platelets > 100 x 109/l, bilirubin < 25 µmol/l or < 1.46 mg/dl, creatinine clearance (calculated or measured) > 60 ml/min
- •- Before patient randomization, written informed consent must be given according to ICH/GCP and national/local regulations.
- •Are the trial subjects under 18? no
- •Number of subjects for this age range:
- •F.1.2 Adults (18-64 years) yes
- •F.1.2.1 Number of subjects for this age range
- •F.1.3 Elderly (>=65 years) yes
- •F.1.3.1 Number of subjects for this age range
排除标准
- •- Small cell, clear cell and other rare variants of the classical adenocarcinoma
- •- prior irradiation or chemotherapy
- •- previous or concurrent second malignancy except for adequately treated basal cell carcinoma of the skin
- •- any psychological, familial, sociological or geographical condition potentially hampering compliance with the study protocol and follow-up schedule; those conditions should be discussed with the patient before registration in the trial
- •- pregnant
研究者
相似试验
进行中（未招募）
1 期
Randomized phase III study of neoadjuvant chemotherapy followed by surgery vs. concomitant radiotherapy and chemotherapy in FIGO Ib2, IIa > 4 cm or IIb cervical cancer.Cervical carcinoma (including squamous cell carcinoma, adenosquamous cell or adenocarcinomaMedDRA version: 16.0Level: LLTClassification code 10008242Term: Cervical carcinoma stage IBSystem Organ Class: 100000004864MedDRA version: 16.0Level: LLTClassification code 10008244Term: Cervical carcinoma stage IIASystem Organ Class: 100000004864MedDRA version: 16.0Level: LLTClassification code 10008245Term: Cervical carcinoma stage IIBSystem Organ Class: 100000004864EUCTR2008-003396-52-GBEuropean Organisation for Research and Treatment of Cancer686
进行中（未招募）
1 期
A study to test the effect of chemotherapy before surgery compared to surgery alone in patients with high risk retroperitoneal sarcomaEUCTR2019-003543-30-ITEORTC AISBL/IVZW250
进行中（未招募）
1 期
A study to test the effect of chemotherapy before surgery compared to surgery alone in patients with high risk retroperitoneal sarcomaPrimary high risk leiomyosarcoma or Liposarcoma ofretroperitoneal space or infra-peritoneal spaces of pelvisMedDRA version: 20.0Level: PTClassification code 10073135Term: Dedifferentiated liposarcomaSystem Organ Class: 10029104 - Neoplasms benign, malignant and unspecified (incl cysts and polyps)MedDRA version: 21.1Level: PTClassification code 10024189Term: LeiomyosarcomaSystem Organ Class: 10029104 - Neoplasms benign, malignant and unspecified (incl cysts and polyps)EUCTR2019-003543-30-FREuropean Organisation for Research and Treatment of Cancer250
进行中（未招募）
1 期
A study to test the effect of chemotherapy before surgery compared to surgery alone in patients with high risk retroperitoneal sarcomaEUCTR2019-003543-30-CZEuropean Organisation for Research and Treatment of Cancer250
进行中（未招募）
1 期
A study to test the effect of chemotherapy before surgery compared to surgery alone in patients with high risk retroperitoneal sarcomaPrimary high risk leiomyosarcoma or Liposarcoma ofretroperitoneal space or infra-peritoneal spaces of pelvisMedDRA version: 20.0Level: PTClassification code 10073135Term: Dedifferentiated liposarcomaSystem Organ Class: 10029104 - Neoplasms benign, malignant and unspecified (incl cysts and polyps)MedDRA version: 21.1Level: PTClassification code 10024189Term: LeiomyosarcomaSystem Organ Class: 10029104 - Neoplasms benign, malignant and unspecified (incl cysts and polyps)EUCTR2019-003543-30-SKEuropean Organisation for Research and Treatment of Cancer250