Trial evaluating the clinical efficacy of cefixime for treatment of early syphilis in non-pregnant women

niversidade de Fortaleza0 个研究点目标入组 210 人开始时间: 2019年4月26日最近更新: 2023年5月29日

适应症

试验速览

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•Female, 18 years of age or older; non-pregnant; able to provide informed consent; test positive for syphilis with a positive TPPA and an RPR titer equal to or greater than 1:8; non-cephalosporin allergic; non-penicillin allergic; agree to be called once a day by study staff to be reminded to take study drug; able to swallow pills; willing to attend follow-up visits at 3, 6, and 9 months after completion of the study treatment; willing to take oral contraceptive or use condom to prevent pregnancy during the
•study period; HIV negative

•Female under 18 years of age; HIV positive; pregnancy test positive or clinical pregnancy; prior history of syphilis or syphilis treatment within 6 months of study screening; allergy to penicillin or cephalosporins (including allergy to cefixime); in the judgment of the interviewer, has a medical condition or other factor that might affect their ability to follow the protocol; previous enrollment in the study; presenting a condition that would not allow reliable informed consent (alcohol abuse or substance misuse); lacking mental capacity to give informed consent to participation.

发起方

niversidade de Fortaleza