NCT05310123Unknown2 期
Investigation of AC-11® Supplementation in Reversing Epigenetic Markers of Biological Aging Including Those Related to Telomere Length
TruDiagnostic1 个研究点 分布在 1 个国家目标入组 32 人开始时间: 2021年5月26日最近更新:
适应症
干预措施
试验速览
- 阶段
- 2 期
- 发起方
- 入组人数
- 32
- 试验地点
- 1
- 主要终点
- Methylation age clock testing
研究概览
简要总结
This is a prospective non-randomized clinical study of 24 patients to evaluate the effects of the AC-11®. The study will evaluate the effectiveness of the supplement's ability to reverse epigenetic markers of biological age. The duration of the study will be 6 months.
研究设计
- 研究类型
- Interventional
- 分配方式
- Na
- 干预模型
- Single Group
- 主要目的
- Prevention
- 盲法
- None
入排标准
- 年龄范围
- 55 Years 至 —（Adult, Older Adult）
- 性别
- All
- 接受健康志愿者
- 是
入选标准
- •Men and women of any ethnicity.
- •Age Range 55 years and older
- •The patient must be able to comply with the treatment plan and laboratory tests
排除标准
- •Neoplastic cancer within 5 years prior to screening, except for cutaneous basal cell or squamous cell cancer resolved by excision
- •No immune system issues or immunodeficiency disease
- •No history of viral illness which could be reactivated by immune downregulation
- •Presence of clinically significant acute or unstable cardiovascular and cerebrovascular (stroke)
- •Diagnosis of a transient ischemic attack in the 6 months prior to screening
- •Patients infected with hepatitis C or HIV
- •Patients with Body Mass Index (BMI) > 40 kg/m2
- •Presence of active infection
- •Any other illness, psychiatric disorder, alcohol or chemical dependence that in the opinion of the investigator would render a patient unsuitable to participate in the study
- •Unable or unwilling to provide a required blood sample for testing
- •As for the male-participants they are recommended to avoid fertilization for the first 6 months after the clinical trial.
- •If the patient has previously used AM/PM HealthSpan system supplements at any time before the start of the trial.
研究组 & 干预措施
AC-11
Experimental
6 months of treatment with AC-11
干预措施: AC-11 (Dietary Supplement)
结局指标
主要结局
Methylation age clock testing
时间窗: Change in epigenetic age from baseline to 6 months
Epigenetic testing
Telomere Test
时间窗: Change in telomere length from baseline to 6 months
Epigenetic testing
次要结局
未报告次要终点
研究者
研究点 (1)
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