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Clinical Trials/NCT06574074
NCT06574074
Active, not recruiting
Not Applicable

Optimizing a Community-based Intervention to Improve Help-seeking for Depression Care in Morang District of Nepal

Transcultural Psychosocial Organization Nepal1 site in 1 country286 target enrollmentJuly 15, 2024

Overview

Phase
Not Applicable
Intervention
Not specified
Conditions
Help-Seeking Behavior
Sponsor
Transcultural Psychosocial Organization Nepal
Enrollment
286
Locations
1
Primary Endpoint
Change in help-seeking behaviour for depression care
Status
Active, not recruiting
Last Updated
last year

Overview

Brief Summary

Depression is a serious public health concern worldwide due to its high prevalence rate and significant emotional and financial burden on individuals, their families, and society. There is a substantial gap between the number of people in need of treatment for depression and those who actually receive it. The recent World Health Organization (WHO) World Mental Health Survey revealed that 86.3% of people with anxiety, mood, or substance disorders in lower-middle-income countries did not receive any treatment in the past 12 months. This study aims to evaluate a community-based intervention to address demand-side barriers by improving mental health literacy, dispelling myths and misconceptions about depression, changing negative attitudes towards depression care, and promoting help-seeking behavior.

Detailed Description

It is estimated that more than 300 million people worldwide are experiencing depression, which is about 4.4% of the world's population. Despite the availability of evidence-based treatment, it is reported that 86.3% of people with anxiety, mood, or substance disorders in lower-middle-income countries received no treatment in the past 12 months. Among people who receive treatment for depression, only one out of 27 persons receive minimally adequate treatment in low- and middle-income countries (LMICs). Despite being the major contributor to the overall global burden of disease, depression receives less or no health priority in many LMICs, where more than 80% of people with depression reside. This study will take place in two municipalities in Morang district, eastern Nepal. Female Community Health Volunteers will administer the intervention to individuals identified with depression using the locally developed and validated Community Informant Detection Tool (CIDT). Participants who receive the intervention will be followed up after one month to evaluate their help-seeking behavior (primary outcome) and after three months to assess treatment adherence, a secondary objective of the study. The study will assess the effects and interactions of four intervention components (information on depression, available treatments, stigma and myths, and life transformation experiences) on the primary outcome of help-seeking behavior and secondary outcomes such as treatment adherence. The severity of depression symptoms will be assessed using the validated PHQ-9, and knowledge and attitudes toward depression will be evaluated to assess mediation effects.

Registry
clinicaltrials.gov
Start Date
July 15, 2024
End Date
November 30, 2024
Last Updated
last year
Study Type
Interventional
Study Design
Factorial
Sex
All

Investigators

Sponsor
Transcultural Psychosocial Organization Nepal
Responsible Party
Sponsor

Eligibility Criteria

Inclusion Criteria

  • being an adult aged 18 or older residing in Kanepokhari Rural Municipality or Patharisanischare Municipality,
  • those detected through the CIDT
  • providing consent for participation
  • being proficient in speaking and understanding Nepali

Exclusion Criteria

  • people with already receiving mental health services
  • having severe mental illness\]
  • participants below the age of 18 years,
  • participants outside of Kanepokhari and Pathari-sanischare Municipality

Outcomes

Primary Outcomes

Change in help-seeking behaviour for depression care

Time Frame: In one month

The primary outcome of this study is "change in help-seeking behavior for depression care, defined by the proportion of participants who receive treatment from a health provider".

Secondary Outcomes

  • Treatment adherence for depression(In three month)
  • Change in symptom severity of depression(In three month)
  • Change in knowledge, attitude and perception(In three months)

Study Sites (1)

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