The Effect of Analgesia Methods Applied in Gynecological Cancer Surgeries on Postoperative Analgesia

Completed

• Conditions: Regional Anesthesia Morbidity; Gynecological Cancer Surgery
• Interventions: Procedure: Intrathecal morphine administered group, Four quadrant transversus abdominis plane block applied group

• Registration Number: NCT06382376
• Lead Sponsor: Bakirkoy Dr. Sadi Konuk Research and Training Hospital

Brief Summary

The aim of this study is to compare the effectiveness of intrathecal morphine and four-quadrant transversus abdominis plane block applied for postoperative analgesia in gynecological cancer surgeries.

The key question(s) it aims to answer are:

\[Is intrathecal morphine more effective in postoperative analgesia?\] Patients who underwent gynecological cancer surgery were examined retrospectively. The investigators evaluated the effect of intrathecal morphine and four-quadrant transversus abdominis plane block applied for postoperative analgesia on pain scores and postoperative opioid use.

Detailed Description

Our study was designed retrospectively. The investigators evaluated analgesia methods in patients who underwent laparoscopic or open surgery due to gynecological cancer between June 2023 and December 2023. The investigators evaluated the effect of intrathecal morphine and four-quadrant transversus abdominis plane block on postoperative analgesia and opioid use.

Group 1: Intrathecal morphine administered group Group 2: Four quadrant transversus abdominis plane block applied group

Study Timeline

• Study Start: 2023-06-01
• Primary Completion: 2023-12-01
• Study Completion: 2024-03-01
• Status Verified: 2024-04
• Study First Submitted: 2024-04-20
• Study First Submitted QC: 2024-04-20
• Study First Posted: 2024-04-24
• Last Update Submitted: 2024-04-24
• Last Update Posted: 2024-04-26

Recruitment & Eligibility

• Status: COMPLETED
• Sex: Female
• Target Recruitment: 71

Inclusion Criteria

• 18 years

  • Patients who have undergone gynecological cancer surgery

Exclusion Criteria

• <18 years
• Those with missing data

Study & Design

• Study Type: OBSERVATIONAL
• Study Design: Not specified

Arm && Interventions

Group	Intervention	Description
Group 1: Intrathecal morphine administered group	Intrathecal morphine administered group, Four quadrant transversus abdominis plane block applied group	Group 1: Intrathecal morphine administered group
Group 2: Four quadrant transversus abdominis plane block applied group	Intrathecal morphine administered group, Four quadrant transversus abdominis plane block applied group	Group 2: Four quadrant transversus abdominis plane block applied group

Primary Outcome Measures

Name	Time	Method
postoperative numerical rating scale	24 hours postoperatively	Our primary aim was to evaluate numerical rating scale at 24 hours postoperatively. numerical rating scale(NRS) was used to assess postoperative pain. NRS values were recorded For example, 0-10 where 0 is no pain and 10 is the worst pain imaginable.

Secondary Outcome Measures

Name	Time	Method
postoperative opioid use	24 hours postoperatively	Our secondary aim was to evaluate opioid demand and consumption amounts in the postoperative 24 hours.

Trial Locations

Locations (1)

Başakşehir Çam and Sakura City Hospital; 🇹🇷 Istanbul, Basaksehir, Turkey