Validation of the French Adaptation of the MSWDQ-23 Questionnaire

Completed

• Conditions: Multiple Sclerosis
• Interventions: Other: questionnaires

• Registration Number: NCT04860791
• Lead Sponsor: Centre Hospitalier Universitaire de Nice

Brief Summary

MS is an autoimmune disease of the central nervous system that affects more than 120,000 people in France. The average age of onset of the disease is between 25 and 35 years. Given the wide range of ages of the patients, from 4 to 80 years, the ethical and socio-economic stakes are high in order to maintain their autonomy, sociability, family and intimate life, and their employment in the best possible conditions and for as long as possible.

However, to date, there are no evaluation tools in French that allow us to understand the difficulties at work of MS patients.

The Multiple Sclerosis Work Difficulties Questionnaire (MSWDQ-23) was developed specifically for MS patients and validated in English \[1\]. There is a short version of this questionnaire that facilitates its use in clinical practice \[2\]. It has been translated and validated in Spanish through a multicenter study, and is currently being validated in German, but does not currently exist in French \[3\]. The main objective of the WORKSEP project is to validate the French version of this questionnaire through a multicenter population-based cohort within the framework of the French-speaking Multiple Sclerosis Society (SFSEP). This validation study will involve the inclusion of 206 French-speaking MS patients, regardless of their professional status, all forms of MS combined, from the early stage (Clinically Isolated Syndrome) to the more advanced stages (primary and secondary progressive forms).

Detailed Description

Not available

Study Timeline

• Study First Submitted: 2021-04-23
• Study First Submitted QC: 2021-04-23
• Study First Posted: 2021-04-27
• Study Start: 2021-05-10
• Primary Completion: 2023-05-31
• Study Completion: 2023-05-31
• Status Verified: 2024-02
• Last Update Submitted: 2024-02-02
• Last Update Posted: 2024-02-05

Recruitment & Eligibility

• Status: COMPLETED
• Sex: All
• Target Recruitment: 206

Inclusion Criteria

• Age between 18 and 65 years old.
• Native French speaker.
• A diagnosis of Clinically Isolated Syndrome or MS defined according to the 2017 McDonald criteria.
• Be affiliated with the social security system.
• Agree to participate in the study.

Exclusion Criteria

Opposition to the use of the data

Study & Design

• Study Type: OBSERVATIONAL
• Study Design: Not specified

Arm && Interventions

Group	Intervention	Description
Multiple Sclerosis patients	questionnaires	-

Primary Outcome Measures

Name	Time	Method
MSWDQ-23 score	1 day	total score out of 100

Trial Locations

Locations (16)

Rouen univestity hospital; 🇫🇷 Rouen, France

Libourne hospital; 🇫🇷 Libourne, France

Strasnourg university hospital; 🇫🇷 Strasbourg, France

Caen university hospital; 🇫🇷 Caen, France

Gonesse hospital; 🇫🇷 Gonesse, France

Nimes university hospital; 🇫🇷 Nîmes, France

Besancon University Hospital; 🇫🇷 Besançon, France

Lyon University Hospital; 🇫🇷 Lyon, France

Groupement des Hôpitaux de l'Institut Catholique de Lille; 🇫🇷 Lomme, France

Marseille University Hospital; 🇫🇷 Marseille, France

Nancy Hospital; 🇫🇷 Nancy, France

Bordeaux university hospital; 🇫🇷 Bordeaux, France

Clermont Ferrand university hospital; 🇫🇷 Clermont-Ferrand, France

Lille University Hospital; 🇫🇷 Lille, France

APHP; 🇫🇷 Paris, France

Saint Etienne University Hospital; 🇫🇷 Saint-Étienne, France