Effects of Breathing Training on Psychosocial Functioning and Heart Rate Variability in Postmenopausal Women With Depressive Symptoms-3
Overview
- Phase
- Not Applicable
- Intervention
- Not specified
- Conditions
- Postmenopause
- Sponsor
- National Science Council, Taiwan
- Locations
- 1
- Primary Endpoint
- Depressive symptoms
- Status
- Withdrawn
- Last Updated
- 11 years ago
Overview
Brief Summary
The specific aims of this study are:
- To develop a breathing training protocol specifically designed to improve HRV and psychosocial functioning for postmenopausal women with depressive symptoms,
- To examine the immediate effects of an 8-week breathing training program on HRV and psychosocial end points in postmenopausal women with depressive symptoms,
- To examine the intermediate-term effects of an 8-week breathing training program on HRV and psychosocial end points in postmenopausal women with depressive symptoms, and
- To determine whether the change in depressive symptoms with breathing training in postmenopausal women is associated with the change in HRV.
Detailed Description
Postmenopausal women without hormone replacement therapy are associated with higher risk of cardiac morbidity and mortality. They are likely to experience depressive symptoms after menopause, and the comorbidity of depression are related to altered autonomic function. We expect that postmenopausal women with depressive symptoms who receive breathing training will demonstrate decreased depressive symptoms and increased heart rate variability immediately upon and later after completion of training, and optimally contributing to improve autonomic nervous regulation in their later life to prevent undesired cardiac outcomes.
Investigators
Pei-Shan Tsai
Professor, College of Nursing, Taipei Medical University
National Science Council, Taiwan
Eligibility Criteria
Inclusion Criteria
- •Permanent termination of menstruation of natural cause.
- •Cessation of menstrual cycles for more than 12 consecutive months.
- •A score of the Chinese version of Beck Depression Inventory-II of greater than
- •Able to speak Mandarin or Taiwanese.
- •Age from 45 to 64 years.
Exclusion Criteria
- •Subjects who are clinically diagnosed with history of cardiac arrhythmia, coronary heart disease, heart failure, kidney disease, hypertension, chronic low blood pressure, diabetic neuropathy, psychosis, mental deficiency.
- •Subjects who received hormone replacement therapy prescribed by gynecological physicians.
- •Subjects who took cardiac and/or psychotropic medications which may affect the autonomic functions
Outcomes
Primary Outcomes
Depressive symptoms
Time Frame: follow-up (16 weeks from baseline)
Secondary Outcomes
- Heart rate variability (Resting, reactivity to stress, and recovery from stress)(follow-up (16 weeks from baseline))