Characterization of the Clinical, Biological and Histological Pulmonary and Renal Damage Associated With the SARS-CoV-2 Syndrome in Patients Admitted in the Intensive Care Unit
Overview
- Phase
- Not Applicable
- Intervention
- Not specified
- Conditions
- Acute Respiratory Distress Syndrome
- Sponsor
- University Hospital, Strasbourg, France
- Enrollment
- 320
- Locations
- 1
- Primary Endpoint
- Analysis of Clinical, Biological and Histological Pulmonary and Renal Impairment Related to SARS-CoV-2
- Last Updated
- 5 years ago
Overview
Brief Summary
Renal damage in patients hospitalized for ARDS in the ICU can also be related to multiple causes including, but not limited to, the consequences of hemodynamic fluctuations in these patients or the use of nephrotoxic drugs responsible for acute post-ischemic or toxic tubular necrosis. Frequently observed abnormalities of cioagumation may also have a potential impact on renal structures, particularly glomerular capillaries.
The researchers wish to characterize and phenotype the renal impairment of patients hospitalized in intensive care with tables of severe Covid19 infections in ARDS: clinical, biological and histological (by performing post-mortem biopsies).
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Investigators
Eligibility Criteria
Inclusion Criteria
- •Patients over 18 years of age
- •Diagnosed Covid-19 by RT PCR
- •Hospitalized in intensive care for management of complications related to Covid-19 from March 1, 2020 to April 20, 2020
- •Patient not having expressed his or her opposition, after information, to the re-use of his or her data for the purposes of this research.
Exclusion Criteria
- •Subject who expressed opposition to participating in the study
Outcomes
Primary Outcomes
Analysis of Clinical, Biological and Histological Pulmonary and Renal Impairment Related to SARS-CoV-2
Time Frame: 1 month