TRAIN-BW: Backward Walking Training in Multiple Sclerosis
Overview
- Phase
- Not Applicable
- Intervention
- Not specified
- Conditions
- Multiple Sclerosis
- Sponsor
- Wayne State University
- Enrollment
- 90
- Locations
- 1
- Primary Endpoint
- Sway during quiet stance
- Status
- Active, not recruiting
- Last Updated
- 4 months ago
Overview
Brief Summary
Individuals with multiple sclerosis (MS) experience in impairments in mobility and cognition that increase the risk for accidental falls. More than 50% of individuals with MS experience injurious falls within a 6-month period. Current interventions to improve fall risk have focused on forward walking (FW) and balance training, resulting in small declines in the relative risk for falls with a large degree of variability. Interestingly, motor differences between MS and healthy controls are more pronounced in backward walking (BW), yet no studies have investigated BW training as an intervention to reduce fall risk in persons with MS. This study will investigate the feasibility, acceptability and impact of BW training compared to forward walking training on motor function and fall risk in persons with MS.
Investigators
Nora Fritz
Associate Professor
Wayne State University
Eligibility Criteria
Inclusion Criteria
- •Diagnosis of MS
- •PDDS \<6, indicating ability to ambulate with or without an assistive device \>/= 50% of the time
- •Self-reported walking dysfunction as evidenced by a score of \>/= 30 on MSWS-12 OR reports of 2 or more falls in the prior 6 months, indicating a frequent faller.
Exclusion Criteria
- •MS relapse within the past 30 days
- •comorbid neurological disorder
- •acute orthopedic disorder/injury
- •unable to follow study-related commands
Outcomes
Primary Outcomes
Sway during quiet stance
Time Frame: Change in sway at 8 weeks
Measured with APDM Sensors
Stepping latency on push-and-release test
Time Frame: Change in stepping latency at 8 weeks
Measured with APDM Sensors
Secondary Outcomes
- Number of Active Minutes(Change in Physical Activity measures at 8 weeks)
- Number of Falls(6 months)
- Forward and Backward Velocity and Double Support Time(Change in velocity and double support time at 8 weeks)
- Client Satisfaction Questionnaire (CSQ-8)(8 weeks)
- ABC Scale(Change in balance confidence at 8 weeks)
- Patient Global Impression of Change(8 weeks)