pathology research of secondary osteoporosis in adult patients with type 2 diabetes mellitus: bone microarchitecture assessed by HR-pQCT

Not Applicable

Recruiting

• Conditions: type 2 diabete mellitus

• Registration Number: JPRN-UMIN000031382
• Lead Sponsor: agasaki University Hospital Department of Endocrinology and Metabolism

Brief Summary

Not available

Detailed Description

Not available

Study Timeline

• Results First Posted: 1900-01-01
• Study Start: 2018-04-01
• Last Update Posted: 17 October 2023
• Study Completion: 2025-12-31

Recruitment & Eligibility

• Status: Recruiting
• Sex: All
• Target Recruitment: 240

Inclusion Criteria

Not provided

Exclusion Criteria

1.a patient with type 1 diabetes mellitus 2.a patinet with thyroid disease, parathyroid disease, celiac or inflammatory bowel disease, renal dysfunction(defined as eGFR <30ml/min) or liver dysfunction (AST > 3 times the upper limit of normal) 3.a patient who takes current or past treatment for osteoporosis 4.a patient who takes a drug such as steroid, anticonvulsant, Ca, P, Vitamin D, Vitamin K, multivitamin, or hormone replacement therapy 5.a patient with a malignat tumor 6.a patient who is pregnant, may be pregnant, or breastfeed 7.a patient whose alchohol consumption over 20g/day 8.a smoker 9.a patient who participates another clinical research within 6 months 10.a patient who is determined as inappropriate as a subject for other reasons by investigator

Study & Design

• Study Type: Observational
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
We investigate bone microarchitecture assessed by HR-pQCT in adult patients with type 2 diabetes mellitus. And we compare them with healthy subjects.

Secondary Outcome Measures

Name	Time	Method
We compare the relationship between bone microarchitecture and metabolic markers with healthy subjects.