A Comparative Clinical Study on the Therapeutic Effect of Ksharkarma and Agnikarma in Cervical ectopy with special reference to Karnini Yonivyapad
试验速览
- 阶段
- 不适用
- 状态
- 尚未招募
- 发起方
- 入组人数
- 40
- 试验地点
- 1
- 主要终点
- Assessment will be done on the following parameters:
研究概览
简要总结
Cervical ectopy or ectropion is a condition where the squamous epithelium of the ectocervix is replaced by columnar epithelium, which is continuous with the endocervix. Based on sign and symptoms it maybe co-related withKarnini yonivyapad.
According to Acharya Charakadue toAkala pravahana i. e straining during labor in absence of labor pains causes vitiation of Vata. This vitiated Vatamixes with ShleshmaandRaktaproduces Karnikain yoni.
According to Acharya Sushrut Shleshma and RaktacausesKarniniin yoni which is called as Karnini yonivyapad. The symptoms observed arekandu(itching), picchila(sticky)
Apamarga has Tikta rasa which is *Shodhana, Lekhana, Kledashoshana.*Kshar has the ksharan (to mobilize and remove the deformed body tissue) property.Ksharalso has tridoshaghna, chedana, lekhanaproperties. All these properties results in destruction of overgrown columnar epithelium
In Agnikarma the diseased tissue is treated by inflicting burns on the tissue surface directly.
The heat transferred increases the blood circulation to the affected site thereby increasing the cellular activity and metabolism.Thus promoting epithelization.
Yashtimadhuthe main content has glycyrrhic acid ammonium salt which increases the epithelization.
研究设计
- 研究类型
- Interventional
- 分配方式
- Randomized
- 盲法
- None
入排标准
- 年龄范围
- 25.00 Year(s) 至 40.00 Year(s)（—）
- 性别
- Female
入选标准
- •Married women aged 25to 40 years having cervical ectopy on per speculum examination with complaints like discharges per vaginum, contact bleeding or cervix bleeds on touch.
排除标准
- ••Unmarried Women.
- ••Pregnant women, Post delivery less than and equal to 3 months, Post abortal period less than and equal to 15 days.
- ••Patient who is on hormonal pills.
- ••Women with uncontrolled DM.
- ••Patients having CIN ,Carcinoma of Cervix, Acute/active genital infections, Uterine prolapse grade III and IV •Patient is on chemotherapy / radio therapy for any malignant condition of any organ.
结局指标
主要结局
Assessment will be done on the following parameters:
时间窗: 3 follow ups | (First Follow up on day 7 of main procedure, with 7 days of pichu application. | 2nd and 3rd follow up at weekly interval, without medication)
Area of extent of ectopy
时间窗: 3 follow ups | (First Follow up on day 7 of main procedure, with 7 days of pichu application. | 2nd and 3rd follow up at weekly interval, without medication)
Discharges per vaginum
时间窗: 3 follow ups | (First Follow up on day 7 of main procedure, with 7 days of pichu application. | 2nd and 3rd follow up at weekly interval, without medication)
Bleeding during per speculum examination
时间窗: 3 follow ups | (First Follow up on day 7 of main procedure, with 7 days of pichu application. | 2nd and 3rd follow up at weekly interval, without medication)
Associated symptoms pruritis vulvae,backache
时间窗: 3 follow ups | (First Follow up on day 7 of main procedure, with 7 days of pichu application. | 2nd and 3rd follow up at weekly interval, without medication)
次要结局
- Reduced discharges per vaginum backache,alleviated symptoms and improved quality of life among study participants(3 follow ups)
研究者
Dr Umak Prachi Diliprao
Institute of Medical Sciences BHU