The effects of sugammadex versus neostigmine on postoperative respiratory complications.
试验速览
- 阶段
- 2 期
- 状态
- 尚未招募
- 发起方
- 入组人数
- 100
- 试验地点
- 1
- 主要终点
- post extubation oxygen saturation
研究概览
简要总结
Reversing neuromuscularblockade with sugammadex can eliminate residual paralysis, which has beenassociated with postoperative respiratory complications. This study was plannedwith an aim to study and compare the effects of sugammadex versus neostigmineon postoperative respiratory complications
研究设计
- 研究类型
- Interventional
- 分配方式
- Not Applicable
- 盲法
- Not Applicable
入排标准
- 年龄范围
- 18.00 Year(s) 至 60.00 Year(s)（—）
- 性别
- All
入选标准
- •ASA 1 & 2 Patients undergoing elective surgery under general anaesthesia with duration of less than 4 hours.
排除标准
- •lack of consent from patient preoperative respiratory failure preoperative tracheostomy pregnancy.
结局指标
主要结局
post extubation oxygen saturation
时间窗: post extubation oxygen saturation for 1hour postoperative period | tOf ratio for one hour postoperative period | clinical signs of recovery for one hour postoperative period
tOf ratio
时间窗: post extubation oxygen saturation for 1hour postoperative period | tOf ratio for one hour postoperative period | clinical signs of recovery for one hour postoperative period
clinical signs of recovery
时间窗: post extubation oxygen saturation for 1hour postoperative period | tOf ratio for one hour postoperative period | clinical signs of recovery for one hour postoperative period
次要结局
- respiratory failure requiring non invasive ventilation or tracheal reintubation(till 7 days postoperative)