Intraoral Measurement of Pressure in Preterm Infants
Overview
- Phase
- Not Applicable
- Intervention
- Not specified
- Conditions
- Preterm Infants
- Sponsor
- University Medical Center Goettingen
- Enrollment
- 24
- Locations
- 1
- Primary Endpoint
- Median Pressure reached by any tape of non-invasive ventilation
- Status
- Completed
- Last Updated
- 2 years ago
Overview
Brief Summary
The aim of the study is to show pressure curves in the nasopharynx in non-invasively ventilated and spontaneously breathing premature and newborn babies
Detailed Description
The aim of the investigation is to show the pressure curves in the nasopharynx in non-invasively ventilated and spontaneously breathing premature and newborn babies, with a number large enough for an analysis. For this purpose, the pressure in the nasopharynx of these children is to be measured using a suction catheter, as is usually used to suction off mucus and saliva, and the measured values are to be evaluated with software. This method is a tried and tested method in adults for measuring the pressure conditions in the nasopharynx, which was developed and used by Mr. Olthoff. A possible later clinical application in premature and newborn infants ranges from the measurement of breathing and ventilation to manual control of respiratory support depending on the measured value to automatic triggering and control of a ventilator in the sense of nSIPPV ventilation (non-invasive synchronized intermittent positive pressure ventilation )
Investigators
Helmut Küster
MD, Principal Investigator
University Medical Center Goettingen
Eligibility Criteria
Inclusion Criteria
- •newborns, non-invasive ventilation
Exclusion Criteria
- •Bad clinical condition of the patient (e.g. sepsis)
- •Bleeding tendency
- •Anatomical peculiarities that make it difficult to insert the suction catheter through the nose (e.g. choanal atresia)
- •Lack of acceptance of the probe by the child
- •Proven infection / colonization of the child by a multi-resistant germ (MRGN 2-4, MRSA) or with noro- / adenoviruses
- •Missing / withdrawn consent by the legal guardians
Outcomes
Primary Outcomes
Median Pressure reached by any tape of non-invasive ventilation
Time Frame: 1 year
The pressure reached by non-invasive ventiation (nCPAP or HFT) in neonates of any gestation is measured weekly to collect data on how to correctly set the ventilator.