eurological risk factors in infants having non-cardiac surgery, and their relationship to growth and neurodevelopmental outcome

Not Applicable

Completed

• Conditions: Congenital diaphragmatic hernia; Oesophageal Atresia; Anterior abdominal wall defect (Gastroschisis or exomphalos); Neurological - Other neurological disorders

• Registration Number: ACTRN12610000156088
• Lead Sponsor: Royal Children's Hospital

Brief Summary

Not available

Detailed Description

Not available

Study Timeline

• Results First Posted: 1900-01-01
• Study Start: 2010-02-16
• Last Update Posted: 13 January 2020

Recruitment & Eligibility

• Status: Completed
• Sex: All
• Target Recruitment: 50

Inclusion Criteria

All infants born after 31 completed weeks gestation with either congenital diaphragmatic hernia, oesophageal atresia or anterior abdominal wall defect.

Exclusion Criteria

None.

Study & Design

• Study Type: Observational
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
eurodevelopmental outcome measured by the Bayley-III[Participants will be tested at 24 months of age.]

Secondary Outcome Measures

Name	Time	Method
Evidence of cerebral structural derangement from advanced magnetic resonance (MR) analysis[Preoperatively and post-operatively (4 weeks after surgery)];Evidence of peri-operative disturbance in cerebral function measured by analysis of background pattern on aEEG, or presence of seizures.[Immediately after surgery until sleep wake cycling resumes.]