Regenerative Endodontics for Non-vital Primary Molars

Not Applicable

Completed

• Conditions: Pulp and Periapical Tissue Disease

• Registration Number: NCT05098483
• Lead Sponsor: Ain Shams University

Brief Summary

Non-vital primary molars will be treated with regenerative endodontic idea using different capping materials aiming to replace the necrotic pulp tissue with biological one and to provide perfect seal over the scaffold

Detailed Description

Non-vital primary molars that fulfill the eligibility criteria will be randomly assigned into one of the 3 study groups:

Group 1: conventional root canal treatment Group 2: Regenerative endodontic treatment using MTA Group3: Regenerative endodontic treatment using Biodentine Each group will be followed up for 12 months

Study Timeline

• Study First Submitted: 2021-09-17
• Study First Submitted QC: 2021-10-27
• Study First Posted: 2021-10-28
• Study Start: 2023-09-05
• Status Verified: 2023-10
• Primary Completion: 2024-10-26
• Study Completion: 2024-10-26
• Last Update Submitted: 2025-06-28
• Last Update Posted: 2025-07-01

Recruitment & Eligibility

• Status: COMPLETED
• Sex: All
• Target Recruitment: 39

Inclusion Criteria

• Non-vital mandibular primary second molar.
• Restorable tooth

Exclusion Criteria

• Patients allergic to medicaments or antibiotics necessary to complete the procedure.
• Special Health Care Needs
• Excessive mobility
• Presence of internal or external root resorption.

Study & Design

• Study Type: INTERVENTIONAL
• Study Design: PARALLEL

Primary Outcome Measures

Name	Time	Method
Radiographic measures	12 months	39 children with no furcal radiolucency or presence of internal resorption. (i.e) successful outcome
Clinical measures	12 months	39 children with no pain or swelling (i.e) successful outcomes

Trial Locations

Locations (1)

Mai Mahmoud Hasaballah; 🇪🇬 Giza, Egypt