Acupuncture for the prevention of chronic migraine attacks
- Conditions
- Chronic migraine (CM)Nervous System Diseases
- Registration Number
- ISRCTN13563102
- Lead Sponsor
- Beijing Hospital of Traditional Chinese Medicine
- Brief Summary
2018 Protocol article in https://www.ncbi.nlm.nih.gov/pubmed/29858418 protocol (added 13/05/2019) 2024 Results article in https://pubmed.ncbi.nlm.nih.gov/38860524/ (added 25/06/2024)
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Completed
- Sex
- All
- Target Recruitment
- 60
1. Diagnosed as chronic migraine according to the diagnostic criteria specified by the International Classification of Headache Disorders(International Classification of Headache Disorders-Third edition (beta version) [ICHD-?ß])
2. Aged between 18 and 65 years old
3. No prophylaxis treatments with acupuncture or drugs in the past 3 months
4. Written informed consent provided
1. Tension-type headache, cluster headache, and other primary headaches
2. Relatively severe systemic diseases(cardiovascular disease, acute infectious disease, hematopathy,endocrinopathy, allergy, and methysis)
3. Headache caused by otorhinolaryngology diseases or intracranial pathological changes
4. Secondary headache and other neurological diseases
5. Pregnancy, lactation, or insufficient contraception
Study & Design
- Study Type
- Interventional
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method Monthly number of headache days (any intensity) is measured using the headache diary at baseline period (4 weeks before the beginning of treatment) and 12 weeks.
- Secondary Outcome Measures
Name Time Method 1. Number of days with acute headache medications is measured using headache diary at baseline period (4 weeks before the beginning of treatment) and 12 weeks.<br>2. Migraine Disability is measured using the MIDAS score at baseline, 12 weeks, and 24 weeks.<br>3. Migraine-Specific Quality-of-Life Questionnaire/Headache impact test measured using the MSQ/HIT6 questionnaire at baseline, 12 weeks, and 24 weeks.<br>4. Anxiety is measured using the STAI/BDI-II questionnaires at baseline, 12 weeks, and 24 weeks.