HanYang University Medical Center (HYUMC) Registry

Recruiting

• Conditions: Coronary Artery Disease; Blood Pressure; Coronary Artery Stenosis
• Interventions: Device: percutaneous coronary intervention

• Registration Number: NCT05935397
• Lead Sponsor: Hanyang University Seoul Hospital

Brief Summary

The HYUMC registry is a two-center, real-world registry of percutaneous coronary intervention in patients with coronary artery disease. From January 2012, PCI-treated patients from Hanyang University Seoul Hospitals and Hanyang University Guri Hospitals were enrolled in this registry.

The aim of this registry is to examine the long-term clinical outcomes and identify predictors of adverse outcomes following percutaneous coronary intervention conducted at academic hospitals.

Detailed Description

In the HYUMC registry, the researchers have gathered and assessed various demographic, laboratory, echocardiographic, and angiographic measurements (both on-admission and during follow-up), as well as conducted questionnaires among patients who underwent percutaneous coronary intervention. The primary focus of this registry is to examine the effects of these parameters on long-term clinical outcomes.

Study Timeline

• Study Start: 2012-01-01
• Status Verified: 2023-06
• Study First Submitted: 2023-06-29
• Study First Submitted QC: 2023-06-29
• Last Update Submitted: 2023-06-29
• Study First Posted: 2023-07-07
• Last Update Posted: 2023-07-07
• Primary Completion: 2025-12-31
• Study Completion: 2025-12-31

Recruitment & Eligibility

• Status: RECRUITING
• Sex: All
• Target Recruitment: 5000

Inclusion Criteria

Consecutive patients with CAD who underwent PCI one or more drug eluting stent (DES) with from 2012 at the Division of Cardiology of Hanyang University Seoul Hospital and Hanyang University Guri Hospital, Korea.

Exclusion Criteria

• second or subsequent hospitalization records of patients with multiple admissions
• patients who died during index hospitalization
• patients who treated with first-generation drug eluting stent
• patients with an outpatient follow-up record of less than 6 months
• patients with insufficient medical records.

Study & Design

• Study Type: OBSERVATIONAL
• Study Design: Not specified

Arm && Interventions

Group	Intervention	Description
patients with CAD undergoing PCI	percutaneous coronary intervention	patients with CAD undergoing PCI with second generation DES

Primary Outcome Measures

Name	Time	Method
MACCE (major adverse cardiac and cerebrovascular event)	10-year	the composite of all-cause death, myocardial infarction, stroke, or any revascularization

Secondary Outcome Measures

Name	Time	Method
All-cause death	10-year	death from any cause
Stroke	10-year	neurological deficit resulting from acute focal damage to the central nervous system due to a vascular cause, requiring hospitalization, and confirmed by a neurologist through imaging findings
Any revascularization	10-year	PCI or coronary artery bypass surgery on either target or nontarget vessels
Myocardial infarction,	10-year	presence of clinical symptoms with the presence of electrocardiographic changes, or imaging evidence of new loss of viable myocardium or new regional wall motion abnormalities, in conjunction with elevated levels of cardiac biomarker above the 99th percentile upper reference limit

Trial Locations

Locations (3)

Hanyang University Seoul Hospital; 🇰🇷 Seoul, Korea, Republic of

Hanyang University Guri Hospital; 🇰🇷 Guri, Korea, Republic of

Young-Hyo Lim; 🇰🇷 Seoul, Korea, Republic of