IRCT20230801058996N5
Not yet recruiting
Phase 1
Safety and efficacy of placental mesenchymal stem cells-derived exosomes in severe refractory inflammatory bowel disease patients
Overview
- Phase
- Phase 1
- Intervention
- Not specified
- Conditions
- Not specified
- Sponsor
- Shahid Beheshti University of Medical Sciences
- Enrollment
- 12
- Status
- Not yet recruiting
- Last Updated
- last year
Overview
Brief Summary
No summary available.
Investigators
Eligibility Criteria
Inclusion Criteria
- •Ulcerative colitis and/or Crohn's disease for at least 6 months with refractory, or intolerance, or contraindication to use with monoclonal antibodies
- •Highly active Crohn's disease with a Crohn's disease index greater than 450 and/or a simple endoscopic score \= 8 (or \= 6 for isolated intestinal disease)
Exclusion Criteria
- •Using common immunomodulators in the past 4 weeks
Outcomes
Primary Outcomes
Not specified
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