Mesenchymal stem cells-derived exosomes in severe refractory inflammatory bowel disease patients
Phase 1
- Conditions
- Condition 1: Ulcerative colitis. Condition 2: Crohn's disease.Ulcerative colitisCrohn disease
- Registration Number
- IRCT20230801058996N5
- Lead Sponsor
- Shahid Beheshti University of Medical Sciences
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Pending
- Sex
- All
- Target Recruitment
- 12
Inclusion Criteria
Ulcerative colitis and/or Crohn's disease for at least 6 months with refractory, or intolerance, or contraindication to use with monoclonal antibodies
Highly active Crohn's disease with a Crohn's disease index greater than 450 and/or a simple endoscopic score = 8 (or = 6 for isolated intestinal disease)
Exclusion Criteria
Using common immunomodulators in the past 4 weeks
Study & Design
- Study Type
- interventional
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method
- Secondary Outcome Measures
Name Time Method