NCT05532475已完成不适用
Vitreous Level Of Tumor Necrosis Factor Alpha In Patients With Retinal Vein Occlusion
Kasr El Aini Hospital1 个研究点 分布在 1 个国家目标入组 40 人开始时间: 2022年3月12日最近更新:
适应症
试验速览
- 阶段
- 不适用
- 状态
- 已完成
- 发起方
- 入组人数
- 40
- 试验地点
- 1
- 主要终点
- to assess vitreous level of tumor necrosis factor alpha in retinal vein occlusion and compare it to patient undergoing cataract surgery
研究概览
简要总结
To assess the levels of TNF- α in vitreous samples of patients with retinal vein occlusion prior to administration of intravitreal anti-VEGF and compare them to levels in vitreous samples of normal subjects so as to investigate the association of vitreous tumor necrosis factor with the pathogenesis of retinal vein occlusion.
研究设计
- 研究类型
- Observational
- 观察模型
- Case Control
- 时间视角
- Cross Sectional
入排标准
- 年龄范围
- 18 Years 至 —(Adult, Older Adult)
- 性别
- All
- 接受健康志愿者
- 否
入选标准
- •Any patient with retinal vein occlusion not older than 6 months with no history of Anti-VEGF injection
排除标准
- •Diabetic patients.
- •Other causes of retinal vascular diseases.
- •Patients with history of treatment of retinal vein occlusion.
- •Previous intraocular surgery except cataract surgery performed 6 months before the study.
- •Subjects with severe systemic inflammatory diseases
- •Retinal vein occlusion secondary to retinal vasculitis.
- •All retinal pathologies.
- •Patients receiving Systemic steroids or Immunosuppressive therapy.
结局指标
主要结局
to assess vitreous level of tumor necrosis factor alpha in retinal vein occlusion and compare it to patient undergoing cataract surgery
时间窗: Day 1
次要结局
未报告次要终点
研究者
Mohamed Ahmed Mohamed Attya
Lecturer of ophthalmology- faculty of medicine- Cairo University
Kasr El Aini Hospital
研究点 (1)
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