Vitreous Level Of Tumor Necrosis Factor Alpha In Patients With Retinal Vein Occlusion
Completed
- Conditions
- Retinal Vein Occlusion
- Interventions
- Diagnostic Test: measurement of vitreous level of tumor necrosis factor alpha
- Registration Number
- NCT05532475
- Lead Sponsor
- Kasr El Aini Hospital
- Brief Summary
To assess the levels of TNF- α in vitreous samples of patients with retinal vein occlusion prior to administration of intravitreal anti-VEGF and compare them to levels in vitreous samples of normal subjects so as to investigate the association of vitreous tumor necrosis factor with the pathogenesis of retinal vein occlusion.
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- COMPLETED
- Sex
- All
- Target Recruitment
- 40
Inclusion Criteria
- Any patient with retinal vein occlusion not older than 6 months with no history of Anti-VEGF injection
Exclusion Criteria
- Diabetic patients.
- Other causes of retinal vascular diseases.
- Patients with history of treatment of retinal vein occlusion.
- Previous intraocular surgery except cataract surgery performed 6 months before the study.
- Subjects with severe systemic inflammatory diseases
- Retinal vein occlusion secondary to retinal vasculitis.
- All retinal pathologies.
- Patients receiving Systemic steroids or Immunosuppressive therapy.
Study & Design
- Study Type
- OBSERVATIONAL
- Study Design
- Not specified
- Arm && Interventions
Group Intervention Description cases measurement of vitreous level of tumor necrosis factor alpha patient with retinal vein occlusion control measurement of vitreous level of tumor necrosis factor alpha cataract patient undergoing cataract surgery
- Primary Outcome Measures
Name Time Method to assess vitreous level of tumor necrosis factor alpha in retinal vein occlusion and compare it to patient undergoing cataract surgery Day 1
- Secondary Outcome Measures
Name Time Method
Trial Locations
- Locations (1)
Kasr ALainy University hospital
🇪🇬Cairo, Egypt