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Clinical Trials/NCT02995382
NCT02995382
Withdrawn
Not Applicable

Health-Related Quality of Life in Cases of Anterior Intramuscular Transposition for Cubital Tunnel Syndrome: A Prospective Cohort Study

McMaster University0 sitesApril 2023

Overview

Phase
Not Applicable
Intervention
Not specified
Conditions
Cubital Tunnel Syndrome
Sponsor
McMaster University
Primary Endpoint
Is there improvement in Health Related Quality of Life?
Status
Withdrawn
Last Updated
3 years ago

Overview

Brief Summary

This study aims to determine the Health Related Quality of life (HRQOL) (the physical, mental, emotional and social functioning) of patients with cubital tunnel syndrome following anterior intramuscular transposition, after one year.

Detailed Description

As there are many different surgical procedures to address cubital tunnel syndrome, HRQOL will be used to determine if anterior intramuscular transposition provides patients with positive outcomes. To measure HRQOL 3 specific scales will be administered: 1. A generic scale, the Short Form-36 2. A condition specific scale, the Patient-Rated Ulnar Nerve Evaluation (PRUNE) 3. A utility scale, the EuroQOL, five dimension questionnaire These scales are widely reported in the literature, are valid, reliable and easy to fill out. Using these scales we can determine HRQOL as well as Quality Adjusted Life Years, which, allows us to do a cost-utility analysis (economic evaluation) on this specific procedure. Patients will be asked to fill out the above mentioned questionnaires, as well as perform 2 performance tests (grip strength, and a moving 2-point discrimination test) at the following time points: 1. 1 week prior to surgery 2. 1 day prior to surgery 3. 3 months post surgery 4. 6 months post surgery 5. 12 months post surgery

Registry
clinicaltrials.gov
Start Date
April 2023
End Date
June 2023
Last Updated
3 years ago
Study Type
Interventional
Study Design
Single Group
Sex
All

Investigators

Responsible Party
Sponsor

Eligibility Criteria

Inclusion Criteria

  • Diagnosis of cubital tunnel syndrome confirmed with Electromyography (EMG) testing or Ultrasound imaging
  • Ability to comprehend English and complete health related quality of life questionnaires
  • Willing to provide informed consent
  • Age \> 18 years
  • Not pregnant

Exclusion Criteria

  • Prior ipsilateral cubital tunnel release
  • Evidence of symptomatic clinical double crush syndrome confirmed by EMG/Nerve Conduction Study (NCS)
  • Patients with rheumatoid arthritis, connective tissue disorder, tenosynovitis, or diagnosed neurological condition that could confound the assessment of health-related quality of life with regard to the affected arm and hand

Outcomes

Primary Outcomes

Is there improvement in Health Related Quality of Life?

Time Frame: 1 week and 1 day pre-op & 3, 6, 12 months post op

HRQOL will be determined using 3 questionnaires: a generic widely reported scale (SF-36), a condition specific valid and reliable scale (The PRUNE), and a utility scale EuroQol-5D)

Secondary Outcomes

  • Which Domains of Health Related Quality of Life Improve?(1 week and 1 day pre-op & 3, 6, 12 months post op)
  • Is there improvement in physical performance?(1 week and 1 day pre-op & 3, 6, 12 months post op)

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