Efficacy and Safety of Carbon Dioxide Insufflation During Endoscopy
- Conditions
- Carbon Dioxide Insufflation During Colonoscopy
- Registration Number
- NCT02502136
- Lead Sponsor
- Chang Gung Memorial Hospital
- Brief Summary
The purpose of this study is to assess the differences of safety and efficacy of carbon dioxide insufflation instead of air during sedated or unsedated endoscopy.
- Detailed Description
Total 640 participants who are indicated to accept endoscopic examinations or procedures will be enrolled in this study. The participants will be divided into 2 groups according to the examination field, esophagogastroduodenoscopy group (320 participants) and colonoscope group (320 participants). The participants in each group will be divided into sedated endoscope subgroup and sedated and unsedated endoscope subgroup (each subgroup is inclusive of 160 participants). Carbon dioxide (CO2) or room air will be used randomly to insufflate the bowel lumen during the procedure in each subgroup.
Recruitment & Eligibility
- Status
- COMPLETED
- Sex
- All
- Target Recruitment
- 640
- outpatients referred for panendoscopy or colonoscopy examination
- pregnancy, breast feeding, severe chronic obstructive lung disease or severe heart failure, renal function impairment, inability to understand participant information, a history of abdominal surgery, or refusal to participate in this study
Study & Design
- Study Type
- INTERVENTIONAL
- Study Design
- PARALLEL
- Primary Outcome Measures
Name Time Method the participants' discomfort scale after endoscopy within 24hours
- Secondary Outcome Measures
Name Time Method