Application of Intelligent Insulin Dose Calculation Software in Patients With Insulin Therapy：A Randomized Controlled Intervention Trial
Trial Snapshot
- Phase
- Not Applicable
- Status
- Recruiting
- Sponsor
- Enrollment
- 182
- Locations
- 1
- Primary Endpoint
- Subjects in both groups targeted blood glucose range (TIR) time or ratio.
Study Overview
Brief Summary
Insulin therapy is the mainstream glucose-lowering program for hospital glucose management. Intelligent insulin dose calculation software based on fingertip glucose monitoring is born in response to the situation. A new generation of continuous blood glucose monitoring technology compared with traditional monitoring technology provides more abundant blood sugar change information.The development of the continuous glucose monitoring technology espcially in blood sugar change trend arrow information, the intelligent insulin dose adjustment sequence based on WeChat program is developed. We plan to carry out a randomized controlled study on patients receiving insulin therapy, in which the insulin dose is adjusted according to the information of four blood glucose monitoring points (before meals and before bed), and randomly divided into two groups, one group is adjusted according to the experience of clinicians, the other group is adjusted according to Wechat program, and glucose monitoring is continued for 1 week. bBood glucose control index of TIR , and the incidence of hypoglycemia and hyperglycemia, hospitalization days and cost was observed. This study ihas great clinical value.
Detailed Description
The problems related to blood glucose in non-endocrine departments are becoming more and more serious.Glucose control level is closely related to the prognosis and cost of inpatients. Insulin therapy is the mainstream glucose-lowering program for hospital glucose management. Intelligent insulin dose calculation software based on fingertip glucose monitoring is born in response to the situation. A new generation of continuous blood glucose monitoring technology compared with traditional monitoring technology provides more abundant blood sugar change information.The development of the continuous glucose monitoring technology espcially in blood sugar change trend arrow information, the intelligent insulin dose adjustment sequence based on WeChat program is developed. We plan to carry out a randomized controlled study on patients receiving insulin therapy, in which the insulin dose is adjusted according to the information of four blood glucose monitoring points (before meals and before bed), and randomly divided into two groups, one group is adjusted according to the experience of clinicians, the other group is adjusted according to Wechat program, and glucose monitoring is continued for 1 week. bBood glucose control index of TIR , and the incidence of hypoglycemia and hyperglycemia, hospitalization days and cost was observed. This study ihas great clinical value.
Study Design
- Study Type
- Interventional
- Allocation
- Randomized
- Intervention Model
- Parallel
- Primary Purpose
- Supportive Care
- Masking
- Single (Participant)
Eligibility Criteria
- Ages
- 18 Years to 70 Years (Adult, Older Adult)
- Sex
- All
- Accepts Healthy Volunteers
- No
Inclusion Criteria
- •Non-endocrine departments;
- •Currently using intensive insulin therapy with basic meals;
- •Belong to type 1 or Type 2 diabetes
- •Hospitalized patients
- •Regular meals
Exclusion Criteria
- •Unwilling to participate or unable to cooperate.
- •Myocardial infarction or cardiovascular and cerebrovascular events in the last 3 months;
- •Glomerular filtration rate < 45 ml/min / 1.73 m2;
- •Other serious concomitant diseases;
- •Liver function transaminase is 2 times higher than the upper limit of normal range;
- •Use of oral hypoglycemic drugs other than metformin
- •Asymptomatic hypoglycemia
Outcomes
Primary Outcomes
Subjects in both groups targeted blood glucose range (TIR) time or ratio.
Time Frame: one week
Subjects in both groups targeted blood glucose range (TIR) time or ratio.
Secondary Outcomes
- insulin dose(one week)
- below target blood glucose range (TBR) for time or Proportion(one week)
- Mean blood glucose(one week)
- above target blood glucose range (TAR) for time or ratio,(one week)
- hospitalization cost(one week)
- hospitalization length of stay(one week)
Investigators
xiaolong zhao
director
Huashan Hospital