Biomarkers for Therapy Response in Drug-resistant Tuberculosis
试验速览
- 阶段
- 不适用
- 状态
- 已完成
- 发起方
- 入组人数
- 192
- 试验地点
- 1
- 主要终点
- Identification of biomarkers for therapy response
研究概览
简要总结
Multi-center, observational, prospective cohort study including patients with multidrug-resistant tuberculosis at different sites in Germany.
The aim the study is the identification of biomarkers for therapy response.
详细描述
The increasing rates of multidrug-resistant (MDR) tuberculosis (TB) are causing great concern. The current study that will be conducted at different centers in Germany. Biomarkers for treatment response during the course of the tuberculosis therapy will be evaluated. The study will be conducted with funding of the German Center for Infection Research (DZIF).
研究设计
- 研究类型
- Observational
- 观察模型
- Cohort
- 时间视角
- Prospective
入排标准
- 年龄范围
- 18 Years 至 —（Adult, Older Adult）
- 性别
- All
- 接受健康志愿者
- 是
入选标准
- •Subjects with confirmed pulmonary MDR-TB
- •Subject able and willing to give informed consent
排除标准
- •HIV infection
- •physical or mental inability preventing study participation at the discretion of the investigator
- •member of a vulnerable or special population (prisoner, soldier, mentally ill, under guardianship)
- •age <18 years.
结局指标
主要结局
Identification of biomarkers for therapy response
时间窗: 3 years
次要结局
未报告次要终点
研究者
Christoph Lange
Head of International Health / Infectious Diseases, University Lübeck
Research Center Borstel