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A Phase II study of neoadjuvant combination chemotherapy with TS-1, cisplatin and Paclitaxel (PCS) for resectable advanced gastric cancer.

Phase 2
Conditions
resectable advanced gastric cancer
Registration Number
JPRN-UMIN000006674
Lead Sponsor
Kinki University Faculty of Medicine
Brief Summary

Not available

Detailed Description

Not available

Recruitment & Eligibility

Status
Complete: follow-up complete
Sex
All
Target Recruitment
20
Inclusion Criteria

Not provided

Exclusion Criteria

1) With severe allergy to TS-1, Cisplatin and Paclitaxel 2) Women who are pregnant or breastfeeding. 3) Men who are unwilling to avoid pregnancy. 4) Active infection and inflammation. 5) History of cardiac disease 6) Dyspnea at rest

Study & Design

Study Type
Interventional
Study Design
Not specified
Primary Outcome Measures
NameTimeMethod
response rate
Secondary Outcome Measures
NameTimeMethod
pathological complete response rate recurrence-free survival time progression-free survival overall survival proportion of transit surgery proportion of R0 resection Accomplishment rate down stage rate frequency and grade of adverse postoperative complication frequency and grade of adverse event
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