Randomized Controlled Trial on the Impact of Postoperative Drainage on Nausea and Vomiting After Thyroid- and Parathyroid Surgery
试验速览
- 阶段
- 不适用
- 状态
- 已完成
- 发起方
- 入组人数
- 139
- 试验地点
- 2
- 主要终点
- Assessment of post-operative nausea using visual analogue scale (VAS)
研究概览
简要总结
Wound Drains after Thyroid- and Parathyroid Surgery Impact on Postoperative Nausea and Vomiting (PONV)
详细描述
Postoperative nausea and vomiting (PONV) is common after thyroid surgery. Many patients describe PONV as more irritant in the postoperative course than the endured pain. Postoperative drains are put after thyroid surgery to early recognize bleeding and to collect wound secretion to avoid pressure on the trachea. Whether wound drains do impact on PONV is not known. Therefore, we tested the impact of wound drains on PONV after thyroid- and parathyroid surgery in a randomized controlled clinical trial.
研究设计
- 研究类型
- Interventional
- 分配方式
- Randomized
- 干预模型
- Parallel
- 盲法
- None
入排标准
- 年龄范围
- 18 Years 至 95 Years（Adult, Older Adult）
- 性别
- All
- 接受健康志愿者
- 否
入选标准
- •older than 18 years of age
- •informed consent
- •planed thyroid- or parathyroid resection
- •euthyreostatic preoperative condition
排除标准
- •younger than 18 years of age
- •pregnancy
- •no informed consent
- •retrosternal struma
- •known postoperative nausea and vomiting prior to surgery
- •severe and life threatening systemic health issues
结局指标
主要结局
Assessment of post-operative nausea using visual analogue scale (VAS)
时间窗: 48 hours post surgery
The development of postoperative nausea was determined using a standard visual analogue scale (VAS) with range of 0 to 10. 0 indicated no nausea, 10 indicated very severe nausea. The patients indicated their felt degree of nausea a number between 0 to 10.
Assessment of postoperative vomiting using visual analogue scale (VAS)
时间窗: 48 hours post surgery
The development of postoperative vomiting was determined using a standard Visual analogue scale (VAS) with range of 0 to 10. 0 indicated no nausea, 10 indicated very severe nausea. The patients indicated their felt degree of vomiting indicating a number between 0 to 10. The number of vomiting was counted within the first 48h post surgery
次要结局
- Antiemetic therapy post surgery in patients with and without postoperative drainage(after 48 hours)
研究者
Christoph A. Maurer, MD
Principal investigator
Kantonsspital Liestal