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临床试验/NCT06826651
NCT06826651尚未招募不适用

Thermal Sealing by Bipolar Diathermy Versus Clips Closure of Mesoappendix in Laparoscopic Appendectomy ..A Comparative Study

Assiut University0 个研究点目标入组 100 人开始时间: 2025年3月1日最近更新:
适应症
干预措施

试验速览

阶段
不适用
状态
尚未招募
入组人数
100
主要终点
intraoperative blood loss

研究概览

简要总结

Acute Appendicitis is the most frequent acute pathological abdominal illness needing immediate surgery. The laparoscopic appendectomy (LA) has become more popular and is advised as the first course of treatment, particularly for female, obese, and elderly patients.LA can also give surgeons a greater field view and identification of other abdominal organs that can have different pathologies that could mimic the symptoms of acute appendicitis.The most crucial step in preventing major complications such postoperative bleeding, peritonitis, sepsis is sealing the mesoappendix. Due to this circumstance, surgeons are looking for alternative treatments for LA. The best technique for sealing mesoappendix should be affordable, practical, safe, and easy to apply technically. Extracorporeal sliding knots, intracorporeal ligations, endo-loops, nonabsorbable polymer clips (Hem-o-lock clips), hand-made loops, and Ligasure usage, and bipolar cautery division are some of the techniques utilized at LA to seal mesoappendix. According to studies, each of these techniques is secure and practicable.5 In this study, there is a comparative study between using Bipolar diathermy as a source of sealing and other mechanical closure techniques for mesoappendix To assess effect of energy source sealing of mesoappendix by using Bipolar diathermy in comparison to mechanical closure by clips as regard outcome and complications.

研究设计

研究类型
Interventional
分配方式
Randomized
干预模型
Parallel
主要目的
Treatment
盲法
None

入排标准

年龄范围
18 Years 至 70 Years(Adult, Older Adult)
性别
All
接受健康志愿者
否

入选标准

  • •All patients admitted to AUH with uncomplicated acute appendicitis or chronic appendicitis
  • •Age group (18-70)

排除标准

  • •patients with complex appendicitis (appendicular mass, abscess, etc).
  • •patients who had the following conditions: cirrhosis with ascites, abdominal distention, and coagulation disorders, cardiac patients; shock upon arrival, a large ventral hernia, and inflammatory bowel disease

研究组 & 干预措施

Group A

Experimental

Laparoscopic appendectomy, using of bipolar diathermy to coagulate mesoappendix

干预措施: laparoscopic appendectomy (Procedure)

Group A

Experimental

Laparoscopic appendectomy, using of bipolar diathermy to coagulate mesoappendix

干预措施: bipolar diathermy (Procedure)

Group B

Experimental

laparoscopic appendectomy, using surgical clips in closure of mesoappendix

干预措施: laparoscopic appendectomy (Procedure)

Group B

Experimental

laparoscopic appendectomy, using surgical clips in closure of mesoappendix

干预措施: clips closure (Procedure)

结局指标

主要结局

intraoperative blood loss

时间窗: baseline

amount of blood loss will be calcculated by number of towel used and aomunt of blood in sution

次要结局

未报告次要终点

研究者

申办方类型
Other
责任方
Principal Investigator
主要研究者

Abdulrahman Samir Fahmy Sayed

Resident doctor

Assiut University

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