Percutaneous splanchnic nerve neurolysis vs. endoscopic ultrasound-guided celiac ganglia neurolysis
- Conditions
- Chronic intractable abdominal/back pain inoperable abdominal malignancychronische onhoudbare buik-/rugpijninoperabele maligniteit in buik
- Registration Number
- NL-OMON27412
- Lead Sponsor
- niversity Medical Center Utrecht
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Pending
- Sex
- Not specified
- Target Recruitment
- 94
Inclusion Criteria
•Diagnosis of an inoperable malignant tumor in the abdomen by histopathological or imaging findings.
oInoperable malignancy is defined as local tumor infiltration into surrounding organs, distant metastases or a poor general health due to serious concomitant disease.
Exclusion Criteria
•Previous CPN
•Patients with a poor mental condition or mental retardation, unable to understand the nature and possible consequences of the study
Study & Design
- Study Type
- Interventional
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method The primary parameter is the difference in short-term efficacy between P-SNN and EUS-CGN. <br /><br>•Pain is measured using a 11-point numeric rating scale (0-10) for upper abdominal or back pain. Pain is assessed after seven days, the patient is asked about the pain score with regard to the previous 24 hours. This is compared to the patients baseline pain score in order to determine the reduction in pain (=efficacy).<br /><br>•Baseline pain score is based on an assessment by the patient. The average pain score from the three consecutive days prior to the procedure will be used to determine the baseline pain score. <br>
- Secondary Outcome Measures
Name Time Method