A randomized trial of multifactorial primary prevention in high risk subjects candidate to a lung cancer early detection CT program - SMILE

FONDAZIONE IRCCS ISTITUTO NAZIONALE DEI TUMORI0 个研究点目标入组 2,000 人开始时间: 2021年6月8日最近更新: 2021年8月24日

试验速览

暂无简介。

•Age between 55 and 75 years
•Heavy smoker (=30 packages/year)
•Eligibility to screening with annual chest CT
•Availability and ability to use the Internet via PC, tablet or smartphone
•Ability to understand the project to which you intend to participate
•No tumors in the last 5 years
•Signature of informed consent for enrollment in the study and for the processing of personal data
•Are the trial subjects under 18? no
•Number of subjects for this age range:
•F.1.2 Adults (18-64 years) yes
•F.1.2.1 Number of subjects for this age range 1350
•F.1.3 Elderly (>=65 years) yes
•F.1.3.1 Number of subjects for this age range 650

•Hypersensitivity to acetylsalicylic acid, salicylates or any of the excipients (excipients: cellulose powder, corn starch; coating: copolymers of methacrylic acid, sodium lauryl sulfate, polysorbate 80, talc, triethyl citrate)
•Chronic treatment with cardioASA, or other anti-clotting or anti-coagulant drugs (for example: heparin, dicumarol)
•Treatment with methotrexate
•Existing Mastocytosis
•History of asthma induced by the administration of salicylates or substances to similar activity, particularly non-steroidal anti-inflammatory drugs
•Gastroduodenal ulcer
•Hemorrhagic diathesis
•Severe chronic pathology (eg: severe respiratory and / or renal and / or hepatic and / or cardiac insufficiency)
•Severe kidney failure
•Serious psychiatric problems
•Previous treatment with Cytisine
•Abuse of alcohol or other substances (even before)

发起方