Studying the effect of bone marrow mesenchymal stem cell injection into the subarachnoid space on improvement and reduction of complications in spinal cord injured patients
Phase 1
- Conditions
- Spinal Cord Injury.Injury Of Spinal Cord, Level Unspecified
- Registration Number
- IRCT2013050813267N1
- Lead Sponsor
- Shahid Sadoughi Yazd University Of Medical Sciences, Vice Chancellor for Research
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Complete
- Sex
- All
- Target Recruitment
- 30
Inclusion Criteria
filling the questionnaire by patient and his/her family; age 13-60; no more than 3 months passed from injury date, no history of cancer in patient and his family; no history to other chronic disorder; no other acute disease at present; self control on breathing; no contribution in the other studies; no convulsion and fever; no infectious diseases in patient like AIDS and hepatitis, and meningitis.
Exclusion criteria: patient request; occurrence of fever and convulsion after cell therapy, occurrence of any other complication; infection, instability of patient's health conditions ; worsening of the patient's disease.
Exclusion Criteria
Not provided
Study & Design
- Study Type
- interventional
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method Evaluation of Generation of Ectopic Tissue Such as Tumor After Stem Cell Therapy. Timepoint: Three months after third injection. Method of measurement: MRI; Physical Examination; Biochemical Tests About Presence of Ectopic Tissue or Tumor in Patients.
- Secondary Outcome Measures
Name Time Method Improvement In Somatic Sensation And Control Of Bladder , And Motor Function Improvements. Timepoint: 1 Month. Method of measurement: Physical Examination.