Effect of Stellate Ganglion Block Combined With Facial Nerve Block on the Treatment of Idiopathic Facial Paralysis
试验速览
- 阶段
- 不适用
- 状态
- 已完成
- 发起方
- 入组人数
- 80
- 试验地点
- 1
- 主要终点
- Change from Baseline House-Brackmann
研究概览
简要总结
Peripheral facial palsy is caused by damage to the facial nerve at any site of the peripheral branches after the facial nucleus.Stellate ganglion block is performed to treat peripheral facial palsy because it increases blood flow and promotes nerve regeneration.Facial Nerve Block worked with elimination of local inflammation of nerve and oppression. Facial nerve block is a treatment that inject drugs into the damaged nerve around to eliminate local inflammation and compression of the nerve.
研究设计
- 研究类型
- Interventional
- 分配方式
- Randomized
- 干预模型
- Parallel
- 主要目的
- Prevention
- 盲法
- Triple (Participant, Investigator, Outcomes Assessor)
入排标准
- 年龄范围
- 18 Years 至 75 Years（Adult, Older Adult）
- 性别
- All
- 接受健康志愿者
- 否
入选标准
- •Diagnosed by clinical and neurological assessment as one-sided simple facial
- •Age 18 to 75 years
- •HBGS above Ⅳ
- •the course of IFP not over 7 days.
排除标准
- •Coagulation dysfunction
- •plate plate plate shape, quantity or abnormal function
- •mental system diseases
- •Gillan-Bahrain syndrome
- •cancer, mumps, shingles infection, jaw facial pus lymph nodeitis, encephalitis, -cerebral hemorrhage and other diseases
- •local infection or systemic infectious disease at the puncture site
- •can not accept to nerve block
研究组 & 干预措施
Facial Nerve Block Group
Facial Nerve Block and oral Mecobalamin Tablets
干预措施: Facial Nerve Block (Procedure)
Facial Nerve Block Group
Facial Nerve Block and oral Mecobalamin Tablets
干预措施: Mecobalamin Tablets (Drug)
Stellate Ganglion Block Group
Facial Nerve Block and Stellate Ganglion Block and oral Mecobalamin Tablets
干预措施: Stellate Ganglion Block (Procedure)
Stellate Ganglion Block Group
Facial Nerve Block and Stellate Ganglion Block and oral Mecobalamin Tablets
干预措施: Facial Nerve Block (Procedure)
Stellate Ganglion Block Group
Facial Nerve Block and Stellate Ganglion Block and oral Mecobalamin Tablets
干预措施: Mecobalamin Tablets (Drug)
D Group
Facial Nerve Block
干预措施: Facial Nerve Block (Procedure)
C Group
control
干预措施: Mecobalamin Tablets (Drug)
结局指标
主要结局
Change from Baseline House-Brackmann
时间窗: Baseline ,change from baseline House-Brackmann at 3 days,6 days,9 days,14 days,one month,two month
The House-Brackmann scale is a nerve grading system developed in 1985 by Los Angeles otolaryngologists Dr. John W. House and Dr. Derald E. Brackmann. It is used to characterize the severity of a facial paralysis patient's symptoms.
Change from Baseline Sunnybrook
时间窗: Baseline,change from baseline Sunnybrook at 3 days,6 days,9 days,14 days, one month,two month
Sunnybrook is a new facial nerve function of subjective assessment system.It is based on both static and dynamic aspects.
次要结局
未报告次要终点
研究者
Zhuan Zhang
Clinical Professor
Yangzhou University