Effect of Short-Term Mindfulness-Based Training For Major Depression Disorder: An Eye-Tracking Study

Central South University1 site in 1 country60 target enrollmentSeptember 1, 2019

ConditionsMDD

Overview

Phase: N/A
Intervention: Not specified
Conditions: MDD
Sponsor: Central South University
Enrollment: 60
Locations: 1
Primary Endpoint: Mean Change from Baseline in Eye Movement Performance During Free-View Task at 2 Weeks
Last Updated: 6 years ago

Overview Investigators Eligibility Criteria Outcomes Sites Similar Trials

Overview

Brief Summary

The purpose of this study is to investigate the short-term effects of mindfulness-based training in individuals suffering from major depressive disorder (MDD) as assessed by clinical interviewing, self-report assessment, cognitive evaluation and eye-tracking task.

Registry

clinicaltrials.gov

Start Date

September 1, 2019

End Date

January 2020

Last Updated

6 years ago

Study Type

Interventional

Study Design

Parallel

Sex

All

Investigators

Sponsor

Central South University

Responsible Party

Principal Investigator

Lingjiang Li

President of Chinese Psychiatry Society of Chinese Medical Association

Central South University

Eligibility Criteria

Inclusion Criteria

•Meet Diagnostic and Statistical Manual (DSM-IV) diagnosis of depression
•Consent to participate in the study and to be randomized to one of two groups

Exclusion Criteria

•Current or past substance abuse, psychotic disorder,obsessive compulsive disorder , Post-Traumatic Stress Disorder, in the past 6 months
•History of epilepsy or head trauma
•Eye disorders
•History of electroconvulsive therapy in the past 4 weeks.

Outcomes

Primary Outcomes

Mean Change from Baseline in Eye Movement Performance During Free-View Task at 2 Weeks

Time Frame: at baseline and in 2 weeks

The first fixated location and latency (msec) of each trial, the total dwell time (msec) in each interest area (IA) during the whole trial to assess the attentional bias in the experiment.

Secondary Outcomes

Mean Change from Baseline in State Mindfulness at 2 Weeks(at baseline and in 2 weeks)
Mean Change from Baseline in Tendency to Engage in Ruminative Responses at 2 Weeks(at baseline and in 2 weeks)
Mean Change from Baseline in the Symptoms of Major Depression as Measured by BDI-II at 2 Weeks(at baseline and in 2 weeks)
Mean Change from Baseline in the Symptoms of Major Depression as Measured by HAM-D at 2 Weeks(at baseline and in 2 weeks)