Effect of Short-Term Mindfulness-Based Training For Major Depression Disorder: An Eye-Tracking Study
试验速览
- 阶段
- 不适用
- 发起方
- 入组人数
- 60
- 试验地点
- 1
- 主要终点
- Mean Change from Baseline in Eye Movement Performance During Free-View Task at 2 Weeks
研究概览
简要总结
The purpose of this study is to investigate the short-term effects of mindfulness-based training in individuals suffering from major depressive disorder (MDD) as assessed by clinical interviewing, self-report assessment, cognitive evaluation and eye-tracking task.
研究设计
- 研究类型
- Interventional
- 分配方式
- Randomized
- 干预模型
- Parallel
- 主要目的
- Treatment
- 盲法
- Single (Outcomes Assessor)
入排标准
- 年龄范围
- 18 Years 至 40 Years（Adult）
- 性别
- All
- 接受健康志愿者
- 否
入选标准
- •Meet Diagnostic and Statistical Manual (DSM-IV) diagnosis of depression
- •Consent to participate in the study and to be randomized to one of two groups
排除标准
- •Current or past substance abuse, psychotic disorder,obsessive compulsive disorder , Post-Traumatic Stress Disorder, in the past 6 months
- •History of epilepsy or head trauma
- •Eye disorders
- •History of electroconvulsive therapy in the past 4 weeks.
研究组 & 干预措施
Mindfulness-Based Training
Participants in the Mindfulness-Based Training arm will receive 2 weeks of Mindfulness-Based Training for at least 30 minutes every day.
干预措施: Mindfulness-Based Training (Behavioral)
Relaxation Training
Participants in the Relaxation Training arm will receive 2 weeks of Relaxation Training for at least 30 minutes every day.
干预措施: Relaxation Training (Behavioral)
结局指标
主要结局
Mean Change from Baseline in Eye Movement Performance During Free-View Task at 2 Weeks
时间窗: at baseline and in 2 weeks
The first fixated location and latency (msec) of each trial, the total dwell time (msec) in each interest area (IA) during the whole trial to assess the attentional bias in the experiment.
次要结局
- Mean Change from Baseline in State Mindfulness at 2 Weeks(at baseline and in 2 weeks)
- Mean Change from Baseline in Tendency to Engage in Ruminative Responses at 2 Weeks(at baseline and in 2 weeks)
- Mean Change from Baseline in the Symptoms of Major Depression as Measured by BDI-II at 2 Weeks(at baseline and in 2 weeks)
- Mean Change from Baseline in the Symptoms of Major Depression as Measured by HAM-D at 2 Weeks(at baseline and in 2 weeks)
研究者
Lingjiang Li
President of Chinese Psychiatry Society of Chinese Medical Association
Central South University