Effect of Short-Term Mindfulness-Based Training For Major Depression Disorder: An Eye-Tracking Study
Trial Snapshot
- Phase
- Not Applicable
- Sponsor
- Enrollment
- 60
- Locations
- 1
- Primary Endpoint
- Mean Change from Baseline in Eye Movement Performance During Free-View Task at 2 Weeks
Study Overview
Brief Summary
The purpose of this study is to investigate the short-term effects of mindfulness-based training in individuals suffering from major depressive disorder (MDD) as assessed by clinical interviewing, self-report assessment, cognitive evaluation and eye-tracking task.
Study Design
- Study Type
- Interventional
- Allocation
- Randomized
- Intervention Model
- Parallel
- Primary Purpose
- Treatment
- Masking
- Single (Outcomes Assessor)
Eligibility Criteria
- Ages
- 18 Years to 40 Years (Adult)
- Sex
- All
- Accepts Healthy Volunteers
- No
Inclusion Criteria
- •Meet Diagnostic and Statistical Manual (DSM-IV) diagnosis of depression
- •Consent to participate in the study and to be randomized to one of two groups
Exclusion Criteria
- •Current or past substance abuse, psychotic disorder,obsessive compulsive disorder , Post-Traumatic Stress Disorder, in the past 6 months
- •History of epilepsy or head trauma
- •Eye disorders
- •History of electroconvulsive therapy in the past 4 weeks.
Arms & Interventions
Mindfulness-Based Training
Participants in the Mindfulness-Based Training arm will receive 2 weeks of Mindfulness-Based Training for at least 30 minutes every day.
Intervention: Mindfulness-Based Training (Behavioral)
Relaxation Training
Participants in the Relaxation Training arm will receive 2 weeks of Relaxation Training for at least 30 minutes every day.
Intervention: Relaxation Training (Behavioral)
Outcomes
Primary Outcomes
Mean Change from Baseline in Eye Movement Performance During Free-View Task at 2 Weeks
Time Frame: at baseline and in 2 weeks
The first fixated location and latency (msec) of each trial, the total dwell time (msec) in each interest area (IA) during the whole trial to assess the attentional bias in the experiment.
Secondary Outcomes
- Mean Change from Baseline in State Mindfulness at 2 Weeks(at baseline and in 2 weeks)
- Mean Change from Baseline in Tendency to Engage in Ruminative Responses at 2 Weeks(at baseline and in 2 weeks)
- Mean Change from Baseline in the Symptoms of Major Depression as Measured by BDI-II at 2 Weeks(at baseline and in 2 weeks)
- Mean Change from Baseline in the Symptoms of Major Depression as Measured by HAM-D at 2 Weeks(at baseline and in 2 weeks)
Investigators
Lingjiang Li
President of Chinese Psychiatry Society of Chinese Medical Association
Central South University